A case of ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with AIDS: longitudinal molecular analysis of the CMV viral load and viral mutations in blood …

G Boivin, C Gilbert, M Morissette, J Handfield… - Aids, 1997 - journals.lww.com
… drug-resistant viruses [ 6–8 ]. We report here a case of progressive CMV retinitis in an AIDS
patient treated with … An extensive study of the viral DNA load and resistance-associated viral

Comparison of cytomegalovirus (CMV) UL97 gene sequences in the blood and vitreous of patients with acquired immunodeficiency syndrome and CMV retinitis

…, Cytomegalovirus Retinitis and Viral … - The Journal of …, 2002 - academic.oup.com
… UL97 gene in which ganciclovir-resistant mutations have been found, … , the virus load in the
vitreous of eyes with CMV retinitis may … the longitudinal profile of patients' vitreous and blood

[图书][B] Studies of the natural history of human cytomegalovirus infection in the HIV infected host

EF Bowen - 1997 - search.proquest.com
… used to study the viral fitness of different UL97 mutants and … first progression of retinitis
according to (a) blood viral load at … identification of HCMV ganciclovir resistant isolates. Drew et …

[PDF][PDF] CMV retinitis in HIV-positive patients in the pre-HAART era

FD Verbraak - 1999 - dare.uva.nl
… values of CMV viral load measured in many patients precede … the eye and the blood
compartment. The gB2 genotype was … CMV and the other herpes viruses, or between CMV and …

Cytomegalovirus

PD Griffiths, VC Emery, R Milne - Clinical virology, 2009 - Wiley Online Library
CMV Retinitis The dramatically increased proportion of … This effect is stronger than the
association of HIV viral load with … patients develop disease due to ganciclovir-resistant mutants, …

Analysis of cytomegalovirus UL97 drug resistance mutations in patients receiving Ganciclovir

NP Nkosi - 2018 - open.uct.ac.za
… who show an increase or plateauing of CMV viral load levels … immunocompromised
HIV-infected patients with CMV retinitis who … of a UL97 ganciclovir resistant mutation (L595S). The …

Human cytomegalovirus resistance to antiviral drugs: diagnosis, monitoring and clinical impact

F Baldanti, G Gerna - Journal of Antimicrobial Chemotherapy, 2003 - academic.oup.com
… reported only in patients harbouring ganciclovir-resistant UL97-mutant … patient with AIDS:
longitudinal molecular analysis of the CMV viral load and viral mutations in blood compartments

Human cytomegalovirus resistance to antiviral drugs

C Gilbert, G Boivin - Antimicrobial Agents and Chemotherapy, 2005 - Am Soc Microbiol
… UL97 mutations associated with GCV resistance in blood … HCMV strains restricted to specific
body compartments (44, 84). … for at least 1 week after the viral load becomes undetectable. …

Risk factors for cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome

WG Hodge - 2002 - escholarship.mcgill.ca
CMV viral load may aiso be a useful predictor. GENERAL OBJECTIVE: To determine risk
factors for CMV retinitis in patients with AIDS… in HIV pathogenesis include HIV mutations that …

[HTML][HTML] Antiviral therapy for human cytomegalovirus

PD Griffiths, M Boeckh - Human herpesviruses: biology, therapy …, 2007 - ncbi.nlm.nih.gov
AIDS patients with first episode CMV retinitis have a significantly higher mortality rate if their
CMV viral load in blood is … and found the same mutations in the blood of 11 of these patients, …