… identified two further PKS gene clusters (Bentley et al. 2002; Challis and Hopwood 2003). …
one of these clusters encoding a cryptic modular type I PKS (Cpk cluster) in S. coelicolor, part …

… coelicolor A3(2) produces a yellow compound secreted into the medium. We have proved
… on cpk gene cluster previously described as cryptic type I polyketide synthase cluster. The …

… of Streptomyces coelicolor A3(2) revealed an uncharacterized type I polyketide synthase gene
cluster (cpk). … -specific activator gene apdR of a cryptic PKS-NRPS (nonribosomal peptide …

… we have shown that disruption of type II thioesterase gene scoT from Cpk gene cluster re- …
(2007) A cryptic type I polyketide synthase (cpk) gene cluster in Streptomyces coelicolor A3(2). …

… ScoT associated with polyketide synthase Cpk from Streptomyces coelicolor A3(2) is …
gene cluster of Streptomyces venezuelae was found to have no effect on the level of polyketide …

… the product of cpk cluster remained to be “cryptic.” In 2010, … in the control of cpk gene cluster.
Transcriptional and proteomic … genes cpkA/cpkB/cpkC of the modular polyketide synthase …

… and their gene clusters by natural product class and function, … called polyketide synthases
(PKS) in a Claissen-type acyl … We will also discuss how CPK biosynthesis can be activated. …

… this polyketide is still unclear, we now know that its “cryptic” nature is attributed to a very complex
and precise mechanism of cpk gene cluster … of type I polyketide synthase (PKS I) genes. …

… Streptomyces coelicolor A3(2) designed for the expression of Type III polyketide synthase
(PKS) genes … host for the heterologous expression of Type III PKS gene clusters, we set out to …

… “A second form of the γ-butyrolactone receptor ScbR in Streptomyces coelicolor A3(2) … in
directly regulating a cryptic Type I polyketide biosynthetic gene cluster (cpk cluster) by binding …