… useful method to prevent neurodegeneration in these diseases. In this work, we show that a
highly sulfated CS preparation, CS-E, exerts a neuroprotective effect on neurons treated with …

… A highly sulfated chondroitin sulfate preparation, CS-E, prevents excitatory amino acid-induced
neuronal cell death 高硫酸化コンドロイチン硫酸,CS-Eは,興奮性アミノ酸による神経細胞死を抑制 …

… highly sulfated chondroitin sulfate, CS-E, prevents excitatory amino acid-induced neuronal
cell death … prior to administration of the CS-E preparation, and then examined NMDA-induced …

… Chondroitin sulfate E (CS-E), which is characterized by … Preventing deposition of Aβ oligomers
or fibrils is an important … a key role in Aβ-induced cell death. A large number of studies in …

… negative charged structures that can contribute to reduce local … neurons with a highly
sulfated CS (CS-E) reduced death … neuroprotection in a calcium-overload model of cell death. …

… the CNS where neuronal cell death and neuroinflammation take … 4-sulfated/6-sulfated ratio
(4s/6s ratio–the ratio between the … on each plate were removed with 1 ml of phenolic solution, …

… A highly sulfated chondroitin sulfate preparation, CS-E, prevents excitatory amino acid-induced
neuronal cell death. J Neurochem 2008; 104: 1565-76. [25] Akiyama H, Sakai S, Linhardt …

… effects of chemically sulfonated chondroitin sulfate should be … was only to prepare a
semi-synthetic CS-E with comparable … trimethyamine sulfur trioxide might reduce these side …

… for biosynthesis of highly sulfated chondroitin sulfate CS-E. … CS-E prevents excitatory amino
acid-induced neuronal cell … thus prepared as well as 2.5×10 6 glioblastoma U251-MG cells …

… In our CS-E-containing culture, some growth factors may have been … A highly sulfated
chondroitin sulfate preparation, CS-E, prevents excitatory amino acid-induced neuronal cell death. …