Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity
Q Zhou, GS Salvesen - Biochemical Journal, 1997 - portlandpress.com
… activation we have analysed the processing of pro-caspase-7 by serine proteases with varied
specificities… The caspase-7 zymogen was rapidly activated by granzyme B and more slowly …
specificities… The caspase-7 zymogen was rapidly activated by granzyme B and more slowly …
[PDF][PDF] The caspase family
M Lamkanfi, W Declercq, B Depuydt… - Caspases–their role …, 2002 - ndl.ethernet.edu.et
… 1 In the past years it has become clear that a group of cysteinyl aspartate-specific … Activation
of pro-caspase-7 by serine proteases includs a non-canonical specificity. Biochem J 1997; …
of pro-caspase-7 by serine proteases includs a non-canonical specificity. Biochem J 1997; …
Molecular determinants involved in activation of caspase 7
… Using this method, we obtained specific activities that are 17–… that pro-caspase 7 mutant
LEHD/NDTA was activated by … location has considerable impact on the efficacy of activation…
LEHD/NDTA was activated by … location has considerable impact on the efficacy of activation…
A review on caspases: key regulators of biological activities and apoptosis
G Sahoo, D Samal, P Khandayataray… - Molecular neurobiology, 2023 - Springer
… elegans and CED-4 protein is the stimulator for CED-3 activation while the CED-9 protein is
… zymogens and contain long pro-domains which allow them to interact with specific signalling …
… zymogens and contain long pro-domains which allow them to interact with specific signalling …
Proteases implicated in apoptosis: old and new
KL Moffitt, SL Martin, B Walker - Journal of Pharmacy and …, 2010 - academic.oup.com
… More recently, it has been suggested that serine proteases … AP24, a chymotrypsin-like
serine protease, is activated by a … specific and potent irreversible inhibitors of serine proteases. …
serine protease, is activated by a … specific and potent irreversible inhibitors of serine proteases. …
[PDF][PDF] Engineered hybrid dimers: tracking the activation pathway of caspase-7
… region of procaspase-7. This suggested a possible cooperative mechanism of cleavage
and … Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity. …
and … Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity. …
The protein structures that shape caspase activity, specificity, activation and inhibition
P Fuentes-Prior, GS Salvesen - Biochemical Journal, 2004 - portlandpress.com
… , refers to the number specific for the particular caspase. In addition, we have included in …
caspases in a mechanistic sense closer to serine proteases, in particular those of the subtilisin …
caspases in a mechanistic sense closer to serine proteases, in particular those of the subtilisin …
Noncaspase proteases in apoptosis
DE Johnson - Leukemia, 2000 - nature.com
… on the activation of cellular proteases. Elucidation of the specific proteases involved in …
Key components of these granules are perforin and the granzyme family of serine proteases…
Key components of these granules are perforin and the granzyme family of serine proteases…
[HTML][HTML] Many cuts to ruin: a comprehensive update of caspase substrates
U Fischer, RU Jänicke, K Schulze-Osthoff - Cell Death & Differentiation, 2003 - nature.com
… For full activation, an additional, still unknown serine protease has to intervene. Only the
combined action of both proteases … specificity at aspartic acid is not strictly required for caspase …
combined action of both proteases … specificity at aspartic acid is not strictly required for caspase …
Caspase‐8 and caspase‐7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF‐R1 receptosomes
B Edelmann, U Bertsch, V Tchikov… - The EMBO …, 2011 - embopress.org
… pro‐A‐SMase zymogen at the non‐canonical cleavage site after … It is presently unknown how
A‐SMase and pro‐caspase‐7 … has to be distinguished from the mere catalytic specificity for …
A‐SMase and pro‐caspase‐7 … has to be distinguished from the mere catalytic specificity for …