… AST-120 (Kremezin) is a prominent oral adsorbent that consists of … To evaluate whether
Kremezin can prevent the diarrhea … adsorption characteristics of CPT-11 and its metabolites onto …

… for the prevention and treatment of delayed diarrhea. We … balance of intestinal absorption
to cause diarrhea. Moreover, … Clomiphene is such an orally activated carbon composed of …

… toxicities of irinotecan hydrochloride (CPT‑11) is delayed‑onset diarrhea. CPT… adsorption
of CPT-11 onto oral adsorbent AST-120 (Kremezin) for the prevention of delayed-onset diarrhea…

… AST-120 (Kremezin) is another oral carbonaceous ad… Kremezin has demonstrated
significant adsorption capacity for … Prevention of irinotecaninduced diarrhea by oral sodium …

… Adsorption of irinotecan onto oral adsorbent AST-120 (Kremezin) for preventing delayed
diarrhea. … study on the use of an oral adsorbent to ameliorate irinotecan-induced diarrhoea. …

… AST-120 has been found to be safe and well-tolerated, effective in reducing pain and bloating
in nonconstipated IBS sufferers and to ameliorate irinotecan-induced diarrhoea … absorption…

… ) that has a lower intestinal absorption, thereby reducing the cytotoxicity experienced by the
… for controlling Irinotecan conversion in patients suffering from life-threatening diarrhea as a …

… Phase II clinical trial for prevention of delayed diarrhea with cholestyramine/levofloxacin
in the second-line treatment with irinotecan biweekly in patients with metastatic colorectal …

… Irinotecan, a key chemotherapeutic drug, is activated by … biomarker of patient response to
irinotecan, whereby low activity of … and improving resistance to irinotecan-based therapies. To …

… AST-120 is a spherical carbon adsorbent, 0.2-0.4 mm in diameter… can include constipation,
nausea and diarrhea; however, the … AST-120 acts by adsorbing gut-derived uremic toxin …