Alpha‐1 adrenoceptor subtypes (high, low) in human benign prostatic hypertrophy tissue according to the affinities for prazosin
M Takeda, A Hatano, T Komeyama, T Koizumi… - … prostate, 1997 - Wiley Online Library
… the α1-adrenergic receptor subtypes in human benign prostatic hypertrophy tissue by using
… Scatchard analysis of binding data in human prostatic adenoma revealed curves that were …
… Scatchard analysis of binding data in human prostatic adenoma revealed curves that were …
Alpha1-adrenoceptors in human prostate: characterization and binding characteristics of alpha1-antagonists
S Yamada, C Tanaka, R Kimura, K Kawabe - Life sciences, 1994 - Elsevier
… [3H]prazosin and [3H]bunazosin in human prostate were around 0.2 to 0.6 nM, while [3H]YM617
bound to the alpha 1adrenoceptors with approximately ten times higher affinity than the …
bound to the alpha 1adrenoceptors with approximately ten times higher affinity than the …
Pharmacological characterization of α1‐adrenoceptor subtypes in the human prostate: functional and binding studies
I Muramatsu, M Oshita, T Ohmurs… - British journal of …, 1994 - Wiley Online Library
… Both a,,- and a,,-adrenoceptor subtypes have a high affinity for prazosin. On the … Alpha-1
adrenoceptors in human prostate: characterization and alteration in benign prostatic hypertrophy…
adrenoceptors in human prostate: characterization and alteration in benign prostatic hypertrophy…
Pharmacological Characterization of the UroselectiveAlpha-1 Antagonist Rec 15/2739 (SB 216469): Role of theAlpha-1L Adrenoceptor in Tissue Selectivity, Part I
A Leonardi, JP Hieble, L Guarneri, DP Naselsky… - … of Pharmacology and …, 1997 - ASPET
… of urethral obstruction in benign prostatic hyperplasia. Rec 15/… the affinities for human and
animal alpha-1 subtypes was … of alpha-1 AR antagonists to inhibit [ 3 H]prazosin binding to …
animal alpha-1 subtypes was … of alpha-1 AR antagonists to inhibit [ 3 H]prazosin binding to …
Comparative alpha-1 adrenoceptor subtype selectivity and functional uroselectivity of alpha-1 adrenoceptor antagonists
DJ Martin, P Lluel, E Guillot, A Coste, D Jammes… - … of Pharmacology and …, 1997 - ASPET
… The threealpha-1-adrenoceptor subtypes with high affinity for prazosin, … -induced contractions
of prostatic tissue in vitro. … of drugs for the treatment of prostatic hypertrophy. Evidence for …
of prostatic tissue in vitro. … of drugs for the treatment of prostatic hypertrophy. Evidence for …
Identification of α-1L and α-1A adrenoceptors in human prostate by tissue segment binding
S Morishima, T Tanaka, H Yamamoto, F Suzuki… - The Journal of …, 2007 - Elsevier
… components with different affinities for prazosin and RS-… Benign prostatic hyperplasia is
a common disease in elderly … Pharmacological characterization of the uroselective alpha-1 …
a common disease in elderly … Pharmacological characterization of the uroselective alpha-1 …
A Concise and Useful Guide to Understand How Alpha1 Adrenoceptor Antagonists Work
SB da Silva, SGD Feitosa… - Mini Reviews in …, 2022 - ingentaconnect.com
… This subtype presents a 10 to 100-fold higher affinity for the … subtypes of a hybrid compound
class containing Prazosin and … of alpha 1adrenoceptor subtype mRNAs in human prostate: …
class containing Prazosin and … of alpha 1adrenoceptor subtype mRNAs in human prostate: …
Characterization of α1-adrenoceptor subtypes in prostate and prostatic urethra of rat, rabbit, dog and man
R Testa, L Guarneri, M Ibba, G Strada… - European journal of …, 1993 - Elsevier
… bladder outlet obstruction due to benign prostatic hyperplasia. … Moreover, our data on the
affinity of prazosin, WB4101 and … and functional properties of alpha 1 adrenoceptors and area …
affinity of prazosin, WB4101 and … and functional properties of alpha 1 adrenoceptors and area …
α-Adrenoceptor antagonists in the treatment of benign prostate hyperplasia
M Thiyagarajan - Pharmacology, 2002 - karger.com
… prazosin in functional assays and can be distinguished from the ·1N type by the high-affinity …
and distribution of alpha-1-adrenoceptor subtype mRNAs in human prostate: Comparison of …
and distribution of alpha-1-adrenoceptor subtype mRNAs in human prostate: Comparison of …
Identification of alpha1-adrenoceptor subtypes in the human prostatic urethra
N Taniguchi, Y Ukai, T Tanaka, J Yano… - Naunyn-Schmiedeberg's …, 1997 - Springer
… by open prostatectomy from patients with benign prostatic … , the affinity of prazosin for
a1-adrenoceptors in the human … 1996) Alpha-1 adrenoceptor subtypes in the human female …
a1-adrenoceptors in the human … 1996) Alpha-1 adrenoceptor subtypes in the human female …