Alpha-glucosidase inhibition and molecular docking studies of 1, 2-benzothiazine 1, 1-dioxide based carbohydrazides.
… α-glucosidase inhibitors which help in lowering the blood glucose level. We presented 1,2-benzothiazine
1,1-dioxide derivatives as novel and more potent α-glucosidase inhibitors via …
1,1-dioxide derivatives as novel and more potent α-glucosidase inhibitors via …
… of novel 4-hydroxy-2H-benzo [e][1, 2] thiazine-3-carbohydrazide 1, 1-dioxide derivative as a dual inhibitor of α-glucosidase and α-amylase: Molecular docking …
… -2H-1,2-benzothiazine-3-carbohydrazide 1,1-dioxide) had less … The 3D structure of the
alpha-glucosidase and the alpha-… Based on these consequences, competitive inhibition is the …
alpha-glucosidase and the alpha-… Based on these consequences, competitive inhibition is the …
[HTML][HTML] Synthesis and α-Glucosidase Inhibition Activity of 2-[3-(Benzoyl/4-bromobenzoyl)-4-hydroxy-1,1-dioxido-2H-benzo[e][1,2]thiazin-2-yl]-N-arylacetamides: An …
… In particular, 1,2-benzothiazine 1,1-dioxide based … e][1,2]thiazine-3-carbohydrazide 1,1-dioxide
showed excellent inhibitions … executed molecular docking studies of all the synthesized 1,…
showed excellent inhibitions … executed molecular docking studies of all the synthesized 1,…
In-silico modeling and in-vitro studies of 2, 1-benzothiazine-2, 2-dioxide based hydrazone derivatives as α-glucosidase inhibitors.
… Molecular docking studies were carried out to find out the binding interactions of targeted …
Alphaglucosidase inhibition and molecular docking studies of 1, 2-benzothiazine …
Alphaglucosidase inhibition and molecular docking studies of 1, 2-benzothiazine …
[HTML][HTML] … of Cyclic Sulfonamides with an N-Arylacetamide Group as α-Glucosidase and α-Amylase Inhibitors: Biological Evaluation and Molecular Modeling
… In particular, 1,2-benzothiazine 1,1-dioxide carboxamides (… , the 1,2-benzothiazine-3-carbohydrazides
6 and 7 (Figure 1) … -competitive-type inhibitory effect of alpha-glucosidase, as the …
6 and 7 (Figure 1) … -competitive-type inhibitory effect of alpha-glucosidase, as the …
[HTML][HTML] The antihyperglycemic potential of pyrazolobenzothiazine 1, 1-dioxide novel derivative in mice using integrated molecular pharmacological approach
… compounds were selected based on docking score, bonding … by molecular docking
studies, and we performed enzyme … promising inhibitor for the targeted enzyme, alpha-glucosidase. …
studies, and we performed enzyme … promising inhibitor for the targeted enzyme, alpha-glucosidase. …
Synthesis, molecular docking and anti-diabetic studies of novel benzimidazole-pyrazoline hybrid molecules
… studied by screening them for their α-glucosidase inhibition activity. The SAR was established
through molecular docking … Compound 5d appeared as effective inhibitor with IC50 = 50.06…
through molecular docking … Compound 5d appeared as effective inhibitor with IC50 = 50.06…
[HTML][HTML] Design, Synthesis and Pharmacological Evaluation of 2-(3-BenzoyI-4-Hydroxy-1, 1-Dioxido-2H-Benzo [e][1, 2] thiazin-2-yI)-N-(2-Bromophenyl) Acetamide as …
… assays, enzyme kinetics against alpha-glucosidase and … The 3-benzoyl-4-hydroxy-1,2-benzothiazine
1,1-dioxide (0.5 g, … The relative molecular docking analysis has been performed …
1,1-dioxide (0.5 g, … The relative molecular docking analysis has been performed …
Synthesis, single crystal X-ray, spectroscopic and computational (DFT) studies 2, 1-benzothiazine based hydrazone derivatives
… In this research paper, we report the synthesis of 2,1-… Alpha-glucosidase inhibition and
molecular docking studies of 1,2-benzothiazine 1,1-dioxide based carbohydrazides …
molecular docking studies of 1,2-benzothiazine 1,1-dioxide based carbohydrazides …
[HTML][HTML] Integrating Pharmacological and Computational Approaches for the Phytochemical Analysis of Syzygium cumini and Its Anti-Diabetic Potential
F Rashid, A Javaid, UA Ashfaq, M Sufyan… - Molecules, 2022 - mdpi.com
… atoms of aligned protein and ligand during molecular docking and … two most potent
phytochemicals based on their lowest binding … /alpha-glucosidase (a), gallic acid/alpha-glucosidase …
phytochemicals based on their lowest binding … /alpha-glucosidase (a), gallic acid/alpha-glucosidase …