An integrated approach to prognosis using protein microarrays and nonparametric methods

T Knickerbocker, JR Chen, R Thadhani… - Molecular Systems …, 2007 - embopress.org
… have been developed that address the problem of disease diagnosis. Here, we report an
integrated approach to the problem of prognosis that uses protein microarrays to measure a …

OmicsNPC: applying the non-parametric combination methodology to the integrative analysis of heterogeneous omics data

N Karathanasis, I Tsamardinos, V Lagani - PloS one, 2016 - journals.plos.org
… (c) the integration of RNA-seq and microarray expression profiles … Overall, integrative
approaches performed better in … have reported to affect treatment response in Glioblastoma [66]; …

An integrated approach for the analysis of biological pathways using mixed models

L Wang, B Zhang, RD Wolfinger, X Chen - PLoS Genetics, 2008 - journals.plos.org
… models approach with nonparametric method GSEA and parametric method PAGE using a
… 1, two sets of 50 microarray samples were simulated for treatment and control groups. Each …

Protein microarrays for personalized medicine

X Yu, N Schneiderhan-Marra, TO Joos - Clinical chemistry, 2010 - academic.oup.com
… This review focuses on protein microarray applications for biomarker discovery and validation…
An integrated approach to prognosis using protein microarrays and nonparametric methods

The identification of phosphoglycerate kinase‐1 and histone H4 autoantibodies in pancreatic cancer patient serum using a natural protein microarray

TH Patwa, C Li, LM Poisson, HY Kim, M Pal… - …, 2009 - Wiley Online Library
… rank-based non-parametric statistical testing approach in which proteins eliciting significant
… have utility in cancer diagnosis, in establishing prognosis and in targeted immunotherapy …

Noise filtering and nonparametric analysis of microarray data underscores discriminating markers of oral, prostate, lung, ovarian and breast cancer

VM Aris, MJ Cody, J Cheng, JJ Dermody… - Bmc Bioinformatics, 2004 - Springer
… evaluating treatment efficacy and predicting patient outcome. … This non-parametric method
for marker selection was chosen so … This integrative approach can yield a signature of distinct …

Protein expression profiles in adenocarcinomas and squamous cell carcinomas of the lung generated using tissue microarrays

R Ullmann, P Morbini, I Halbwedl… - The Journal of …, 2004 - Wiley Online Library
… expression of 86 proteins was evaluated and the results were analysed by non-parametric
tests, hierarchical … At present, clinical stage is the most important prognostic indicator. Tissue …

Multi-omics data integration, interpretation, and its application

I Subramanian, S Verma, S Kumar… - … and biology insights, 2020 - journals.sagepub.com
… the tools and methods that adopt integrative approach to analyze … This method uses a
Bayesian nonparametric model (… of integrative approach that helps in advancement of treatment

Finding consistent patterns: a nonparametric approach for identifying differential expression in RNA-Seq data

J Li, R Tibshirani - Statistical methods in medical research, 2013 - journals.sagepub.com
… We introduce a simple, non-parametric method with … from one sample, and using multiple
arrays, expression levels in … quantitative and survival outcomes. The major strength of our …

A technical assessment of the utility of reverse phase protein arrays for the study of the functional proteome in non-microdissected human breast cancers

BT Hennessy, Y Lu, AM Gonzalez-Angulo, MS Carey… - Clinical proteomics, 2010 - Springer
… concentration of each protein on the x-axis using the non-parametric, monotone increasing
B-… c overall survival using the reverse phase protein array (RPPA) signature shown in Fig. 9c …