[HTML][HTML] … and tolerability of THC/CBD oromucosal spray and oromucosal THC spray in patients with terminal cancer-related pain refractory to strong opioid analgesics

JR Johnson, D Lossignol, M Burnell-Nugent… - Journal of pain and …, 2013 - Elsevier
… This study showed that the long-term use of THC/CBD spray was generally well tolerated, …
relief of cancer-related pain with long-term use. Furthermore, patients who kept using the study

Effectiveness and tolerability of THC: CBD oromucosal spray as add-on measure in patients with severe chronic pain: analysis of 12-week open-label real-world data …

MA Ueberall, U Essner… - … of Pain Research, 2019 - Taylor & Francis
patients registered (28.2%) took THC:CBD for cancer-related … prior history of refractory CP
reported by the patients in this … conclusions on the long-term effectiveness of THC:CBD for this …

A review of scientific evidence for THC: CBD oromucosal spray (nabiximols) in the management of chronic pain

MA Überall - Journal of pain research, 2020 - Taylor & Francis
… A subsequent open-label extension study involving 39 patients … , with some patients
maintaining long-term (up to 2 years) … studies in patients with chronic cancer-related or …

Safety and tolerability of nabiximols oromucosal spray: a review of more than 15 years” accumulated evidence from clinical trials

JM Prieto Gonzalez, C Vila Silvan - Expert Review of …, 2021 - Taylor & Francis
… reports safety data from RCTs and related open-label studies … were considered to be
cancer-related and not related to … capsules, dronabinol, nabilone and THC/CBD oral capsules …

[HTML][HTML] … , randomized, placebo-controlled study of nabiximols oromucosal spray as an adjunctive therapy in advanced cancer patients with chronic uncontrolled pain

AH Lichtman, EA Lux, R McQuade, S Rossetti… - Journal of pain and …, 2018 - Elsevier
… in Cannabis sativa L plants, Δ 9 -tetrahydrocannabinol has shown promise in relieving
cancer-related pain.11… Safety and tolerability were assessed by documenting treatment-emergent …

Sativex oromucosal spray as adjunctive therapy in advanced cancer patients with chronic pain unalleviated by optimized opioid therapy: two double-blind …

MT Fallon, E Albert Lux, R McQuade… - … journal of pain, 2017 - journals.sagepub.com
… In another open-label extension study, 15 39 patients who … for the relief of cancer pain with
long-term use and did not seek … advanced cancer patients suffering from cancer-related pain

[HTML][HTML] Effects of cannabinoids on pain control, quality of life and opioid-sparing in cancer patients: systematic review

SS Sá, C Melo-Alvim, P Reis-Pina - BrJP, 2023 - SciELO Brasil
… An open-label extension study to investigate the long-term safety and tolerability of THC/CBD
oromucosal spray and … cancer-related pain refractory to strong opioid analgesics. J …

[PDF][PDF] … -blind, randomized, placebo-controlled study of Sativex oromucosal spray as adjunctive therapy in advanced cancer patients with chronic uncontrolled pain

A Lichtman, AE Lux, R McQuade… - Journal of Pain and …, 2018 - research.ed.ac.uk
Cancer-related pain is estimated to occur in up to 60% of … ®) is an oral mucosal spray
formulated from Cannabis sativa L … Safety and tolerability were assessed by documenting …

[HTML][HTML] Clinical research evidence supporting administration and dosing recommendations of medicinal cannabis as analgesic in cancer patients

C Christensen, M Allesø, M Rose, C Cornett - Journal of Clinical …, 2022 - mdpi.com
cannabis to patients suffering from cancer-related pains. Only clinical … open-label extension
study to investigate the long-term safety and tolerability of THC/CBD oromucosal spray

… , safety, and tolerability of nabiximols oromucosal spray vs typical oral long-acting opioid analgesics in patients with severe neuropathic back pain: Analysis of 6-month …

MA Ueberall, C Vila Silván, U Essner… - Pain …, 2022 - academic.oup.com
… or second-line therapy or for long-term treatment [1]. Nevertheless, … This was a retrospective,
open-label, parallel-group, flexible-… of patients with active cancer and/or cancer-related pain; …