… that the (±)-cis-(6-ethyl-tetrahydropyran-2-yl)-formic acid (tetrahydropyran derivative) produces
potent antinociceptive effects in acute nociceptive and inflammatory pain in mice. These …

… Mice were tested according to Eddy and Leimback. The animals tail were placed on a water
… This substance developed a maximal effect increasing the antinociceptive activity in 40% …

… to the (Æ) cis (6-ethyl-tetrahydropyran-2-yl) formic acid (1) using the … This new compound
presented a significant antinociceptive … Mice were tested according to Eddy and Leimback.The …

… synthesis of (±)-cis-(6-ethyl-tetrahydropyran-2-yl) formic acid (2a), 6 and for the (−)-(S,S)-2b …
The antinociceptive activity of 2a was evaluated in mice on acetic acid-induced abdominal …

… the synthesis and effect of (±)-cis-(6-ethyl-tetrahydropyran-2-yl) formic acid. This compound
… the mice develop tolerance to the antinociceptive effects of CTHP and morphine, mice were …

… of (±)-cis-(6-ethyl-tetrahydropyran-2-yl) formic acid (1a) [5], and for the (-)–(S,S)–1b … The
antinociceptive activity of 1a was evaluated in mice on acetic acid-induced abdominal writhing, …

… antinociceptive activity tested in mice and compared with morphine sulphate. All compounds
demonstrated antinociceptive activity … The studies showed that the antinociceptive activity is …

… treatment mice were tolerant to the analgesic effect of … effect was observed only after 7 days
of consecutive treatment. Nevertheless, mice retained an effect and the antinociceptive effect …

… The aim of this study was to evaluate the antinociceptive and … prototype acid, (±) - cis- (6-ethyltetrahydropyran-2-yl)
Formic. The … was able to induce antinociceptive activity in models of …

… That way, we performed in vitro evaluation for anticancer activity against cancer cell lines,
such as the … Other studies corroborate with our results, demonstrating increased activity of …