… response, we examined the antinociceptive activities of various fatty acid ethanolamide
analogs of palmitylethanolamide. Oleylethanolamide (shorthand fatty acid designation, 18:1Δ 9 …

… Related endogenous fatty acid derivatives such as oleamide, palmitoylethanolamide, 2-…
is founded in preclinical studies demonstrating antinociceptive effects of cannabinoid receptor …

… Oleoylethanolamide (OEA) is a natural fatty acid amide that mainly … The analgesic activity
of OEA was measured against … and structurally related to the endogenous cannabinoid …

… Palmitoylethanolamide (PEA), an endogenous fatty acid amide … acid, kaolin, MgSO4, and
capsaicin and in hot plate [11] and tail flick tests [25], AEA has a powerful antinociceptive action…

… hypothesis that PEA is an endogenous mediator whose levels are … to exert a local anti-inflammatory
and analgesic action. … PMSF is an inhibitor of fatty acid amide hydrolase (FAAH), and …

… Also, primary fatty acid amides, including the amide of oleic acid, which acts as a sleep-…
of the cannabinoid receptor-inactive N -acylethanolamines and primary fatty acid amides. …

… (PEA), an endogenous fatty acid amide analogue of the … the anti-inflammatory and
antinociceptive effects of PEA are in … with anti-inflammatory and antinociceptive activity, such as …

… endogenous ligands for the cannabinoid receptors. Activation of cannabinoid receptors by
endocannabinoids produces antinociception [17… first to document antinociceptive effects of the …

… Brain enzymatic activity of FAAH and the endogenous levels of its substrates, anandamide
(… that the antinociceptive activity of ST4070 may be ascribed to a concurrent action on both CB …

… mast cell activity has led to the application of this fatty acid amide in … A wide range of analgesic
medications are currently … the view of PEA as an endogenous anti-inflammatory agent. In …