Anxiolytic effects of the melatonin MT2 receptor partial agonist UCM765: Comparison with melatonin and diazepam
… Here we used a novel MT 2 -selective partial agonist, UCM765 to evaluate the involvement
… the anxiolytic-like effect of the novel selective MT 2 receptor partial agonist UCM765 and MLT…
… the anxiolytic-like effect of the novel selective MT 2 receptor partial agonist UCM765 and MLT…
Role of melatonin MT2 receptors in the regulation of sleep and anxiety disorders
R Ochoa-Sanchez - 2014 - search.proquest.com
… V Anxiolytic effects of the melatonin MT2 receptor partial agonist UCM765: comparison with
melatonin and diazepam … and anxiolyticlike effects of the novel MT2 receptor partial agonist …
melatonin and diazepam … and anxiolyticlike effects of the novel MT2 receptor partial agonist …
Antinociceptive properties of selective MT2 melatonin receptor partial agonists
M López-Canul, S Comai, S Domínguez-López… - European journal of …, 2015 - Elsevier
… agonists UCM765 and UCM924 were tested in two well-… Anxiolytic effects of the
melatonin MT(2) receptor partial agonist UCM765: Comparison with melatonin and diazepam …
melatonin MT(2) receptor partial agonist UCM765: Comparison with melatonin and diazepam …
CCNP Award Paper: Unveiling the role of melatonin [MT. sub. 2] receptors in sleep, anxiety and other neuropsychiatric diseases: a novel target in …
… effects of UCM765 on the power spectra across the 24-hour period, we found that, unlike the
benzodiazepine diazepam, … demonstrate that the anxiolytic effects of UCM765 and MLT are …
benzodiazepine diazepam, … demonstrate that the anxiolytic effects of UCM765 and MLT are …
CCNP Award Paper: Unveiling the role of melatonin MT2 receptors in sleep, anxiety and other neuropsychiatric diseases: a novel target in psychopharmacology
… found that, unlike the benzodiazepine diazepam, the EEG power of … The MT 2 receptor partial
agonist UCM765 increases the … MT 1 and MT 2 receptors were implicated in the anxiolytic …
agonist UCM765 increases the … MT 1 and MT 2 receptors were implicated in the anxiolytic …
Melatonin, selective and non-selective MT1/MT2 receptors agonists: differential effects on the 24-h vigilance states
… selective MT 2 receptor partial agonist (MT 1 receptors: pK i … profile to the MT 2 receptor but
unlike UCM765 it is more … both MLT and UCM765 produced anxiolytic-like effects at the same …
unlike UCM765 it is more … both MLT and UCM765 produced anxiolytic-like effects at the same …
Investigational melatonin receptor agonists
R Hardeland - Expert opinion on investigational drugs, 2010 - Taylor & Francis
… Anxiolytic and antidepressant effects of melatonin have been … sleep and interference with
diazepam in rotarod assays have … UCM765 exhibited higher receptor affinities than melatonin, …
diazepam in rotarod assays have … UCM765 exhibited higher receptor affinities than melatonin, …
11 MT2 Melatonin Receptors
… MT1 and MT2 receptors were implicated in the anxiolytic properties of MLT, we found that
when UCM765 and MLT … agonist UCM765: Comparison with melatonin and diazepam. Prog …
when UCM765 and MLT … agonist UCM765: Comparison with melatonin and diazepam. Prog …
Targeting melatonin MT2 receptors: a novel pharmacological avenue for inflammatory and neuropathic pain
… of selective MT2 receptor partial agonists (UCM765 and UCM924) [164… Notably, MT2 partial
agonists also display anxiolytic … MT/MT receptor knockout mice and comparison with MT and …
agonists also display anxiolytic … MT/MT receptor knockout mice and comparison with MT and …
[HTML][HTML] Melatonin MT1 and MT2 Receptors Exhibit Distinct Effects in the Modulation of Body Temperature across the Light/Dark Cycle
… the effects of the selective MT 2 receptor partial agonist N-{2-[(… [41], the selective MT 1 receptor
partial agonist N-(2-{Methyl-[3-… The effect of vehicle was compared with that of the different …
partial agonist N-(2-{Methyl-[3-… The effect of vehicle was compared with that of the different …