… Background: This study evaluated whether measuring prothrombin time (PT) using …
apixaban-associated anticoagulant activity in Japanese patients with non-valvular atrial fibrillation (…

… Background:This study evaluated whether measuring prothrombin time (PT) using …
apixaban-associated anticoagulant activity in Japanese patients with non-valvular atrial fibrillation (…

… over time and the association of trough and peak apixaban … of anticoagulant treatment for
each patient with atrial fibrillation. The … partial thromboplastin time (APTT) (Pathromtin SL) and …

… Apixaban at trough and peak, and to evaluate association between PT DOAC expressed in
Clot Time Ratio CTR and clinical outcomes in patients with atrial … run prothrombin time assays…

… However, the Canadian Cardiovascular Society suggests follow-up for reassessment of
therapy at least every 6 months and every 3∼6 months for renal impairment in patients receiving …

… treatment requires frequent monitoring of the international normalized ratio of prothrombin
time (… possible reasons for the lack of association between age and apixaban concentration. …

… observations) favor an association between high rivaroxaban … will be needed for a final
confirmation of this association. … K Antagonist Treatment) trial enrolling apixaban-treated patients …

… for decades [1] but they require regular measurement of prothrombin time or international …
of major bleeding according to the International Society on Thrombosis and Haemostasis (ISTH…

… without substantial association with lower risk of stroke/SE.18 Elevated F1+2 levels have
been described in stroke patients with AF, and as F1+2 levels reflect thrombin generation they …

… PT was measured in a major clinical trial of rivaroxaban versus warfarin for treatment of
nonvalvular atrial fibrillation (the ROCKET AF trial), 15 and the values were used by FDA to …