Association of gastric mucosal injury severity with platelet function and gastric pH during low-dose aspirin treatment

M Nishino, M Sugimoto, T Uotani, M Yamade, S Sahara… - Digestion, 1957 - karger.com
mucosal injury, antiplatelet effects of LDA, and intragastric pH. Methods: We evaluated gastric
injury severity and platelet function … after administration of 100 mg aspirin for 7 days to 18 …

Relationship between low-dose aspirin-induced gastric mucosal injury and intragastric pH in healthy volunteers

M Nishino, M Sugimoto, C Kodaira, M Yamade… - Digestive diseases and …, 2010 - Springer
… might have any association with the intragastric pH. … -1) activity and, thereby, platelet
aggregation, which contributes to the … the severity of aspirin-induced gastric mucosal injury and the …

Dose effects of aspirin on gastric prostaglandins and stomach mucosal injury

M Lee, B Cryer, M Feldman - Annals of internal medicine, 1994 - acpjournals.org
platelet function without causing gastric mucosal injury, we … Aliquots of gastric juice that
had been titrated to pH 7.0 were … of our results is that a low dose of aspirin, such as 3 mg/d or …

Antiplatelet drugs are a risk factor for esophageal mucosal injury

M Sugimoto, T Uotani, M Nishino, M Yamade, S Sahara… - Digestion, 2013 - karger.com
… , 24-hour intragastric pH monitoring and platelet function tests … association with abnormal
acid reflux and esophageal injury … ently healthy subjects treated with low-dose aspirin (ASA) for …

[HTML][HTML] Clinical features of gastroduodenal injury associated with long-term low-dose aspirin therapy

J Iwamoto, Y Saito, A Honda… - World journal of …, 2013 - ncbi.nlm.nih.gov
… with the advent of an aging society. On the other hand, a very … of LDA-induced gastrointestinal
mucosal injury and bleeding … , and impaired platelet aggregation. The pathogenesis …

Association of gastric acid and mucus secretion level with low-dose aspirin-induced gastropathy

K Iijima, N Ara, Y Abe, T Koike, W Iwai… - Journal of …, 2012 - Springer
… the extent of the aspirin-induced gastric mucosal injury varied … surface, which supports the
maintenance of near-neutral pH … that the severity of gastric injury in low-dose aspirin takers …

Effects of very low dose daily, long-term aspirin therapy on gastric, duodenal, and rectal prostaglandin levels and on mucosal injury in healthy humans

B Cryer, M Feldman - Gastroenterology, 1999 - Elsevier
… on aspirin's potential to induce gastrointestinal mucosal injury. … daily aspirin dose that
effectively inhibited platelet COX-1 … using the same scale as was used to score the stomach and …

Risk and preventive factors of lowdose aspirin‐induced gastroduodenal injuries: A comprehensive review

A Shiotani, N Manabe, T Kamada… - Journal of …, 2012 - Wiley Online Library
… , is increased in association with the use of low-dose aspirin (LDA)… A2 for platelet
aggregation.There is genetic diversity … NSAID gastric ulceration: predictive value of gastric pH, …

Impact of acid inhibition on esophageal mucosal injury induced by low-dose aspirin

M Sugimoto, M Nishino, C Kodaira, M Yamade… - Digestion, 1956 - karger.com
… study, with mostly mild severity (eg endoscopic redness alone). … control intragastric pH to
prevent esophageal mucosal injury. … association with occurrence of aspirin-induced esophageal …

Comparison of the degree of gastric mucosal injury between patients who are receiving dual antiplatelet therapy or single antiplatelet therapy

Y Shimada, M Hojo, Y Kita, Y Ikeda, S Sato, A Murata… - Diagnostics, 2022 - mdpi.com
… of gastric mucosal injury in patients taking low-dose aspirin in … pKa 3.5) and in the highly
acidic stomach (pH 1–2) it exists in … the platelet aggregation effect of clopidogrel [25,26], but at