Avian metapneumoviruses expressing Infectious Bronchitis virus genes are stable and induce protection

M Falchieri, C Lupini, M Cecchinato, E Catelli… - Vaccine, 2013 - Elsevier
… subtype A Avian metapneumovirus (AMPV) to accept foreign genes and be … Infectious
bronchitis virus (IBV) QX genes to chickens. Initially the GFP gene was added to AMPV at all gene

Avian Metapneumovirus Reverse Genetics Developments and their Effect on the Performance of Recombinant Live Vaccines

A Laconi - 2016 - amsdottorato.unibo.it
… the inserted genes efficiently and to be stable during passage … Chapter 6 investigates how
to increase the protection induce … seem to have the opposite effect: Infectious bronchitis virus (…

Infectious bronchitis virus evolution, diagnosis and control

M Legnardi, CM Tucciarone, G Franzo… - Veterinary Sciences, 2020 - mdpi.com
… The strategy adopted by coronaviruses in gene expression … live ones in inducing a proper
protection and strong mucosal … IBV providing a chemically stable environment, without altering …

Methyltransferase-defective avian metapneumovirus vaccines provide complete protection against challenge with the homologous Colorado strain and the …

J Sun, Y Wei, A Rauf, Y Zhang, Y Ma, X Zhang… - Journal of …, 2014 - Am Soc Microbiol
viruses share common strategies for viral gene expression … The genetic stability of each
raMPV mutant was determined … with raMPV mutants can induce protective immunity. Briefly, 1-…

BacMam virus-based surface display of the infectious bronchitis virus (IBV) S1 glycoprotein confers strong protection against virulent IBV challenge in chickens

J Zhang, XW Chen, TZ Tong, Y Ye, M Liao, HY Fan - Vaccine, 2014 - Elsevier
… of avian viruses, such as fowlpox virus and metapneumovirus, as transgene vectors mediating
the expression … In this study, BV-Dual-S1 was deficient in the induction of an IBV-specific …

Infectious bronchitis virus poly-epitope-based vaccine protects chickens from acute infection

L Tan, Y Zhang, F Liu, Y Yuan, Y Zhan, Y Sun, X Qiu… - Vaccine, 2016 - Elsevier
… Recently, epitope-based vaccines that are safe, non-infective, stable, and low cost have …
on peptides or virus-induced T cell proliferation. We compared the survival in immune protection

Viral respiratory diseases (ILT, aMPV infections, IB): are they ever under control?

RC Jones - British poultry science, 2010 - Taylor & Francis
Avian metapneumoviruses, the cause of turkey rhinotracheitis … may evade existing vaccine
protection. While conventional … ILTV viruses have stayed remarkably stable over the years …

… of an improved reverse genetics system for avian metapneumovirus (aMPV): A novel vaccine vector protects against aMPV and infectious bursal disease virus

L Meng, Y Chen, M Yu, P Liu, X Qi, X Xue… - Journal of Integrative …, 2024 - Elsevier
… effects induced by the rescue virus and the expression of … subtype C expressing the infectious
bronchitis virus S1 and … the rescued virus rLN16A-vvVP2 provided 100% protection against …

Infectious bronchitis virus S2 expressed from recombinant virus confers broad protection against challenge

H Toro, W Zhao, C Breedlove, Z Zhang… - Avian …, 2014 - meridian.allenpress.com
… , stability (recombination events are rare), easy mass-administration via the drinking water
or by aerosol, and inductionmetapneumovirus subgroup C have been previously generated …

A recombinant La Sota vaccine strain expressing multiple epitopes of infectious bronchitis virus (IBV) protects specific pathogen-free (SPF) chickens against IBV and …

L Tan, G Wen, X Qiu, Y Yuan, C Meng, Y Sun, Y Liao… - Vaccines, 2019 - mdpi.com
… and genetic stability was confirmed by whole genome DNA … induce a high level of immune
responses and full protection of … virus [52], and avian metapneumovirus [53] viral backbones …