Baculovirus-Expressed Constructs Induce Immunoglobulin G That Recognizes VAR2CSA on Plasmodium falciparum- Infected Erythrocytes
… -derived constructs induced immunoglobulin G (IgG) that was reactive with native VAR2CSA
on the surface of infected erythrocytes. Our data show that five of the six VAR2CSA Duffy-…
on the surface of infected erythrocytes. Our data show that five of the six VAR2CSA Duffy-…
Multiple Plasmodium falciparum erythrocyte membrane protein 1 variants per genome can bind IgM via its Fc fragment Fcμ
A Jeppesen, SB Ditlev, V Soroka… - Infection and …, 2015 - Am Soc Microbiol
… Recombinant PfEMP1 constructs used in the present study … with either the VAR2CSA-specific
monoclonal antibody PAM1.… Following induction of var switching, we single-cell sorted IEs …
monoclonal antibody PAM1.… Following induction of var switching, we single-cell sorted IEs …
[HTML][HTML] … composition and expression system on the functional antibody response in the development of a VAR2CSA based Plasmodium falciparum placental malaria …
…, PG Kremsner, JP Chippaux, AJF Luty, P Deloron… - PLoS …, 2015 - journals.plos.org
… that induce a broadly strain-transcending antibody response. … against Plasmodium falciparum
infected erythrocytes 3D7 (A) … similarly to the baculovirus expressed batches. For the E. coli …
infected erythrocytes 3D7 (A) … similarly to the baculovirus expressed batches. For the E. coli …
[HTML][HTML] Several domains from VAR2CSA can induce Plasmodium falciparum adhesion-blocking antibodies
…, SB Ditlev, VV Pinto, M Dahlbäck, G Andersen… - Malaria Journal, 2010 - Springer
… infected erythrocytes expressing FCR3 VAR2CSA and for the … All VAR2CSA constructs were
based on native var2csa and … third epitope was predominantly recognized by the inhibitory …
based on native var2csa and … third epitope was predominantly recognized by the inhibitory …
[HTML][HTML] Full-length recombinant Plasmodium falciparum VAR2CSA binds specifically to CSPG and induces potent parasite adhesion-blocking antibodies
P Khunrae, M Dahlbäck, MA Nielsen… - Journal of molecular …, 2010 - Elsevier
… VAR2CSA is recognized as the leading PAM vaccine candidate… of IgG induced against FV2
in rats, we used erythrocytes … shown to be the construct that induces the strongest parasite-…
in rats, we used erythrocytes … shown to be the construct that induces the strongest parasite-…
[HTML][HTML] Targeted disruption of a ring-infected erythrocyte surface antigen (RESA)-like export protein gene in Plasmodium falciparum confers stable chondroitin 4 …
… var2csa transcription and VAR2CSA surface expression, leading to higher C4S-binding
capacity of infected erythrocytes. … of knobless Plasmodium falciparum infected erythrocytes. …
capacity of infected erythrocytes. … of knobless Plasmodium falciparum infected erythrocytes. …
[HTML][HTML] Differential Induction of Functional IgG Using the Plasmodium falciparum Placental Malaria Vaccine Candidate VAR2CSA
…, M Resende, M Dahlbäck, G Andersen, P Andersen… - PloS one, 2011 - journals.plos.org
… binding of Plasmodium falciparum infected erythrocytes (IE) … expression of VAR2CSA and
sex specific recognition by IgG … with either single VAR2CSA-domain constructs (DBL1x-6ε) or …
sex specific recognition by IgG … with either single VAR2CSA-domain constructs (DBL1x-6ε) or …
Antigen reversal identifies targets of opsonizing IgGs against pregnancy-associated malaria
LH Lambert, JL Bullock, ST Cook, K Miura… - Infection and …, 2014 - Am Soc Microbiol
… antibodies that recognize VAR2CSA on the infected erythrocyte (… Molecular masses of
constructs were confirmed by 4 to 20% … recognized by IgGs from multigravida women and induced …
constructs were confirmed by 4 to 20% … recognized by IgGs from multigravida women and induced …
The NTS-DBL2X Region of VAR2CSA Induces Cross-Reactive Antibodies That Inhibit Adhesion of Several Plasmodium falciparum Isolates to Chondroitin Sulfate A
P Bigey, S Gnidehou, J Doritchamou… - Journal of Infectious …, 2011 - academic.oup.com
… syndrome, Plasmodium falciparum infected erythrocytes (IEs… in women who have acquired
immunoglobulin G (IgG) that … ) or by the baculovirus-expressed recombinant NTS-DBL2X (…
immunoglobulin G (IgG) that … ) or by the baculovirus-expressed recombinant NTS-DBL2X (…
Induction of Adhesion-Inhibitory Antibodies against Placental Plasmodium falciparum Parasites by Using Single Domains of VAR2CSA
MA Nielsen, VV Pinto, M Resende… - Infection and …, 2009 - Am Soc Microbiol
… of Plasmodium falciparum-infected erythrocytes in the placenta… Likewise, high anti-VAR2CSA
immunoglobulin G (IgG) levels … VAR2CSA constructs were based on native FCR3 var2csa …
immunoglobulin G (IgG) levels … VAR2CSA constructs were based on native FCR3 var2csa …