… We investigated whether the amylin receptor antagonist, AC253, neutralizes the … amylin
on hippocampal long-term potentiation (LTP). Furthermore, we examined whether depressed …

… amylin-evoked depression of long-term potentiation (LTP) at Schaeffer collateral-CA1
hippocampal … attributed to its indirect rather than direct effects mediated via the amylin receptor. …

… , manifest as a depression of long-term potentiation (LTP) … Isoflurane blocks NMDA
receptor–mediated induction of LTP … Furthermore, Aβ 1–42 inhibition of LTP is mediated via …

… (Aβ42 MO ) and human amylin were purchased from AnaSpec. … In autaptic hippocampal
neurons we studied the effects of … study to NMDA receptor- and AMPA receptor-mediated EPSC …

… amylin (hAmylin)-induced depression of hippocampal … activity at the amylin receptor and
mediate their beneficial effects… the disruption of hippocampal long term potentiation observed in …

… LTP is induced by Ca 2+ influx through NMDARs and is … receptors (AMPARs) that are
recruited to the synapse via … Thus, direct promotion of AMPAR synaptic depression did not …

… and pathology, decreases in long-term potentiation (LTP), the … ability of Aβ to signal through
amylin receptors also suggests a … on CD68 expression are mediated through AMY R3 , as …

… NGF in the hippocampus can prevent plasticity failure induced by Aβ. Here we show that
lentiviral-mediated hNGF gene expression in the rat hippocampus significantly increases NGF …

… , neuronal receptors such as insulin, amylin and receptor for … -oligomer-mediated neurotoxicity.
Aβ interactions with other … of long-term potentiation (LTP) and facilitation of long-term …

… suggested amylin binding in the hippocampus [83, 87-89]. … to be mediated through the
TRPV4 receptor; as TRPV4 receptor … shares neurotoxic properties with Abeta42 in long-term …