C3′-endo-puckered pyrrolidine containing PNA has favorable geometry for RNA binding: novel ethano locked PNA (ethano-PNA)
A Banerjee, VA Kumar - Bioorganic & medicinal chemistry, 2013 - Elsevier
… aegPNA:RNA duplexes. … novel ethano-locked PNA (ethano-PNA) that is envisaged to confer
conformational constraint on the relatively flexible PNA backbone for favorable RNA binding…
conformational constraint on the relatively flexible PNA backbone for favorable RNA binding…
[HTML][HTML] RNA therapeutics: RNAi and antisense mechanisms and clinical applications
J Chery - Postdoc journal: a journal of postdoctoral research and …, 2016 - ncbi.nlm.nih.gov
… of RNAs deepens, researchers have sought to target RNA … ribose sugar locked in a ring
structure. This modification increases … PNAs bind with greater affinity and specificity to target DNA …
structure. This modification increases … PNAs bind with greater affinity and specificity to target DNA …
Toward the Synthesis of [4.2. 1] di-azabicyclic Systems
CA Gomez - 2015 - digitalcommons.montclair.edu
… target molecules presented are novel compounds that have not been previously … of geometric
isomers that were not separated. 27 was reduced by catalytic hydrogenation in ethanol at …
isomers that were not separated. 27 was reduced by catalytic hydrogenation in ethanol at …
Morpholino antisense oligomers: design, preparation, and properties
J Summerton, D Weller - Antisense and Nucleic Acid Drug …, 1997 - liebertpub.com
… intractable diseases, but in recent years progress has been stymied by technical problems,
most … is an overview of the design, preparation, and properties of Morpholino oligos, a novel …
most … is an overview of the design, preparation, and properties of Morpholino oligos, a novel …