CXCR3 and its ligands in a murine model of obliterative bronchiolitis: regulation and function

BD Medoff, JC Wain, E Seung, R Jackobek… - The Journal of …, 2006 - journals.aai.org
… in gene regulation. We therefore examined the regulation and function of the CXCR3 ligands
… In the present study, we use established murine models of OB (17) to define the expression …

Critical role for CXCR3 chemokine biology in the pathogenesis of bronchiolitis obliterans syndrome

JA Belperio, MP Keane, MD Burdick… - The Journal of …, 2002 - journals.aai.org
… studies of CXCR3 and its ligands in a murine model of … the intragraft recruitment of
CXCR3-expressing mononuclear cells. … to modulate CXCR3 receptor and ligand biology and …

[PDF][PDF] CXCR3 and Its Ligands in a Murine Model

AD Luster, TK Jackobek, LC Ginns, JM Farber - J Immunol, 2006 - Citeseer
… did not affect airway obliteration. These data show that in this murine model of obliterative
bronchiolitis, these chemokines are differentially regulated following transplantation, and that …

[HTML][HTML] Role of CXCR2/CXCR2 ligands in vascular remodeling during bronchiolitis obliterans syndrome

JA Belperio, MP Keane, MD Burdick… - The Journal of …, 2005 - Am Soc Clin Investig
… Alternatively, we cannot completely rule out the possibility of occult infections as a possible
… We used a well-established and reproducible murine model of BOS involving heterotopic …

Cxcr3 and its ligand CXCL10 are expressed by inflammatory cells infiltrating lung allografts and mediate chemotaxis of T cells at sites of rejection

C Agostini, F Calabrese, F Rea, M Facco… - The American journal of …, 2001 - Elsevier
… of obliterative bronchiolitis in the heterotopic mouse trachea … In a murine model it has been
shown that CCL5 and … , whereas up-regulation of macrophage inflammatory protein-2 (MIP-2α/…

[HTML][HTML] CXCR3 chemokine ligands during respiratory viral infections predict lung allograft dysfunction

SS Weigt, A Derhovanessian, E Liao, S Hu… - American Journal of …, 2012 - Elsevier
… chemoattractant/ITAC) in regulating leukocyte trafficking to the … We and others have also
demonstrated that CXCR3/ligand … of RSV LRTI incubated with isotype control antibody (mouse

CXCR3 ligands: redundant, collaborative and antagonistic functions

JR Groom, AD Luster - Immunology and cell biology, 2011 - Wiley Online Library
… The tight correlation between CXCR3 expression and Th1 and … in mouse models, that
CXCR3 and its ligands regulate the … In a murine model of obliterative bronchiolitis, CXCL9 and …

Activation of eosinophil CCR3 signaling and eotaxin using a bioinformatics analysis of a mouse model of obliterative airway disease

A Dosanjh - Journal of Interferon & Cytokine Research, 2014 - liebertpub.com
… a role for eosinophil activation in immune-regulated fibrotic … Expression of the chemokine
receptor CXCR3 and its ligand … A humanmouse chimeric model of obliterative bronchiolitis after …

Chemokine receptors and their therapeutic opportunities in diseased lung: far beyond leukocyte trafficking

T Tomankova, E Kriegova… - American Journal of …, 2015 - journals.physiology.org
… of biological functions, including regulation of hematopoiesis … In a mouse model of bronchiolitis
obliterans syndrome (BOS), … suggest that CXCR3 receptor and its ligands are protective …

Long-term exposure of chemokine CXCL10 causes bronchiolitis-like inflammation

D Jiang, J Liang, R Guo, T Xie, FL Kelly… - American Journal of …, 2012 - atsjournals.org
… Studies also suggested that blockage of CXCR3 or its ligands … In a mouse model, deletion
of CXCR3, but not deletion of … with the development of obliterative bronchiolitis after lung …