Cellular and molecular correlates of ectopic activity in patients with atrial fibrillation
… potentially underlying ectopic activity. Below we focus on the molecular correlates of
abnormal cellular impulse generation as a potential basis for ectopic activity in cAF patients. …
abnormal cellular impulse generation as a potential basis for ectopic activity in cAF patients. …
Cellular and molecular electrophysiology of atrial fibrillation initiation, maintenance, and progression
… molecular mechanisms promoting ectopic activity around the PVs in humans is difficult because
of the limited availability of PV tissue from patients… correlates with atrial fibrosis in patients…
of the limited availability of PV tissue from patients… correlates with atrial fibrosis in patients…
Electrophysiological and molecular mechanisms of paroxysmal atrial fibrillation
… 1), although the precise clinical correlates of these fundamental … Atrial fibrillation is initiated
and maintained by focal ectopic … involves premature or rapid ectopic activity. Numerous risk …
and maintained by focal ectopic … involves premature or rapid ectopic activity. Numerous risk …
Molecular and cellular mechanisms of atrial fibrosis in atrial fibrillation
S Nattel - JACC: Clinical Electrophysiology, 2017 - jacc.org
… correlated with AF recurrence after cardioversion: higher PNP concentrations are associated
with electrocardiographic indexes of abnormal atrial conduction and correlate with AF …
with electrocardiographic indexes of abnormal atrial conduction and correlate with AF …
Molecular basis of electrical remodeling in atrial fibrillation
DR Van Wagoner, JM Nerbonne - Journal of molecular and cellular …, 2000 - Elsevier
… pacing model, tribute to ectopic atrial pacemaker activity. The increase in the If message was
… activity. Thus, in addition to considering the role that the molecular correlate of canine IKur …
… activity. Thus, in addition to considering the role that the molecular correlate of canine IKur …
Molecular basis of atrial fibrillation pathophysiology and therapy: a translational perspective
… Atrial fibrous-tissue content is increased in patients with pAF and atrial scarring correlates
with … At the same time, spontaneous atrial ectopic activity seems to be an important trigger for …
with … At the same time, spontaneous atrial ectopic activity seems to be an important trigger for …
Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation
… RyR2 dysregulation may represent the cellular correlates of the clinically observed focal
ectopic (triggered) activity that triggers and may even maintain AF recurrences in pAF patients. …
ectopic (triggered) activity that triggers and may even maintain AF recurrences in pAF patients. …
Molecular determinants of cardiac fibroblast electrical function and therapeutic implications for atrial fibrillation
… in AF patients with identifiable cardiac diseases, 6,7 but also in those with lone AF. There is
a positive correlation … coupling to cardiomyocytes causes atrial ectopic activity or reentry that …
a positive correlation … coupling to cardiomyocytes causes atrial ectopic activity or reentry that …
Cellular electrophysiology of atrial fibrillation
RF Bosch, S Nattel - Cardiovascular research, 2002 - academic.oup.com
… molecular structure of many ion channels involved in cardiac excitability and their functional
correlation … delayed afterdepolarization-induced ectopic activity. A preliminary report in …
correlation … delayed afterdepolarization-induced ectopic activity. A preliminary report in …
The clinical profile and pathophysiology of atrial fibrillation: relationships among clinical features, epidemiology, and mechanisms
… 38 A strong correlation between older age … atrial early afterdepolarization–related
ectopic activity. Mutations altering connexin expression or function lead to AF by altering cell-to-cell …
ectopic activity. Mutations altering connexin expression or function lead to AF by altering cell-to-cell …