Challenges in Identifying New Antimicrobial Agents Effective for Treating Infections with Acinetobacter baumannii and Pseudomonas aeruginosa
LB Rice - Clinical infectious diseases, 2006 - academic.oup.com
… and enterococcal isolates from infections in patients housed in … Pseudomonas aeruginosa
and Acinetobacter baumannii have developed resistance to multiple antimicrobial agents …
and Acinetobacter baumannii have developed resistance to multiple antimicrobial agents …
Unexpected challenges in treating multidrug-resistant Gram-negative bacteria: resistance to ceftazidime-avibactam in archived isolates of Pseudomonas aeruginosa
ML Winkler, KM Papp-Wallace, AM Hujer… - Antimicrobial agents …, 2015 - Am Soc Microbiol
… revealed the importance of this finding in the introduction of novel agents that target P. …
antimicrobial agents, we propose a novel strategy for treatment of dangerous MDR infections …
antimicrobial agents, we propose a novel strategy for treatment of dangerous MDR infections …
Recent trends and challenges to overcome Pseudomonas aeruginosa infections
A Ammazzalorso, A Granese… - Expert Opinion on …, 2024 - Taylor & Francis
… To develop new efficacious antimicrobial agents, it is necessary to know the pathways …
mechanisms of virulence and antibacterial resistance is crucial to identify new biological targets. …
mechanisms of virulence and antibacterial resistance is crucial to identify new biological targets. …
Multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii: resistance mechanisms and implications for therapy
… to antimicrobial drugs currently used for the treatment of … baumannii; however, Spanish
researchers have identified … Considering the issues presented previously, we will further discuss …
researchers have identified … Considering the issues presented previously, we will further discuss …
[HTML][HTML] Developing new therapeutic approaches for treating infections caused by multi-drug resistant Acinetobacter baumannii: Acinetobacter baumannii therapeutics
P Gallagher, S Baker - Journal of Infection, 2020 - Elsevier
… , Acinetobacter baumannii, Pseudomonas aeruginosa, and … baumannii infections, there is
mounting pressure to find new … While A.baumannii remains a major public health challenge …
mounting pressure to find new … While A.baumannii remains a major public health challenge …
Prospects and challenges of developing new agents for tough Gram-negatives
AL Meyer - Current opinion in pharmacology, 2005 - Elsevier
… of Pseudomonas aeruginosa isolates to these same antibiotics … entirely new targets for
antibacterial drugs could be identified, … cost of developing a new antibacterial agent is not justified …
antibacterial drugs could be identified, … cost of developing a new antibacterial agent is not justified …
[HTML][HTML] New Drugs for the Treatment of Pseudomonas aeruginosa Infections with Limited Treatment Options: A Narrative Review
… It is intrinsically resistant to many antimicrobial agents and additional acquired … to
ceftolozane-tazobactam has been identified in P. … aeruginosa, in challenging clinical situations …
ceftolozane-tazobactam has been identified in P. … aeruginosa, in challenging clinical situations …
[HTML][HTML] Recent advances in therapeutic targets identification and development of treatment strategies towards Pseudomonas aeruginosa infections
DRA Sanya, D Onésime, G Vizzarro, N Jacquier - BMC microbiology, 2023 - Springer
… Bacterial biofilms still remain a challenge to the healthcare system due to their resilience
against antimicrobial agents and immune system. Moreover, mechanisms involved in biofilm …
against antimicrobial agents and immune system. Moreover, mechanisms involved in biofilm …
[HTML][HTML] Treatment options for K. pneumoniae, P. aeruginosa and A. baumannii co-resistant to carbapenems, aminoglycosides, polymyxins and tigecycline: an …
… , Pseudomonas aeruginosa and Acinetobacter baumannii. Several treatment options are …
[23, 24], allowing even earlier identification of the mechanisms of resistance and targeted …
[23, 24], allowing even earlier identification of the mechanisms of resistance and targeted …
[HTML][HTML] Acinetobacter baumannii Resistance: A Real Challenge for Clinicians
…, LA Padró Alonzo, A Rivera Reséndiz… - Antibiotics, 2020 - mdpi.com
… baumannii, with the objective of identifying the most … that effectively escape the effects
of antibacterial drugs [16]. … such as Pseudomonas aeruginosa, Acinetobacter baumannii, …
of antibacterial drugs [16]. … such as Pseudomonas aeruginosa, Acinetobacter baumannii, …