… Liver Fibrosis project was a consortium devised to develop non-invasive biomarkers of
liver fibrosis… The result of this research was the enhanced liver fibrosis (ELF™) test, a blood-…

… biopsy remains the gold standard for evaluation of hepatic fibrosis, non-invasive imaging
and measurement of serum parameters will lead to fundamental changes in diagnosis …

… liver fibrosis. The authors also showed low levels of another serological biomarker of collagen
formation predicted patients with a spontaneous regression liver fibrosis phenotype. Study …

… liver fibrosis, preferably with non-invasive methods. Additionally, regression of advanced
fibrosis should be the primary hepatic … and collagen deposition, thereby causing liver fibrosis (80…

… with non-invasive biomarkers as an assessment method of liver damage and liver fibrosis
in … Type IV collagen is the third collagen serving as a direct marker. It acts as a surrogate …

… the extent of hepatic fibrosis [36, 40–42]. At a cutoff level of ≥5.0 ng/mL type VI collagen had
an AUC of … Sebastiani, “Non-invasive assessment of liver fibrosis in chronic liver diseases: …

… and cross-linked fibrolytic biomarkers may improve the … liver disease patients. Herein,
we assessed the role of the novel CTX-III biomarker in assessing cross-linked type III collagen …

… and biomarkers and eventually the replacement of liver biopsy by biomarkers for staging liver
fibrosis. … Serum laminin and type IV collagen are accurate markers of histologically severe …

… progression from collagen bands to bridging fibrosis to frank cirrhosis occurs [7]. In …
Detection of novel biomarkers of liver cirrhosis by proteomic analysis. Hepatology 2009; 49(4):1257-…

… problem of the development of biomarkers capable of non-invasive staging of fibrosis in the
… by the collagen rich fibers [7] and the production of fibrous bands [8]. In advanced stages of …