[HTML][HTML] Common variant in the HMGA2 gene increases susceptibility to nephropathy in patients with type 2 diabetes
… HMGA2 variant seems to be associated with increased risk of developing nephropathy in
patients with type 2 diabetes and with lower eGFR in both diabetic and non-diabetic individuals …
patients with type 2 diabetes and with lower eGFR in both diabetic and non-diabetic individuals …
[HTML][HTML] Recent advances in the molecular genetics of type 2 diabetes mellitus
… , including retinopathy, nephropathy and cardiovascular … which the associated gene may
increase susceptibility to T2DM is … that if a genetic variant confers a high susceptibility to T2DM …
increase susceptibility to T2DM is … that if a genetic variant confers a high susceptibility to T2DM …
[HTML][HTML] miR-98-5p alleviated epithelial-to-mesenchymal transition and renal fibrosis via targeting Hmga2 in diabetic nephropathy
Y Zhu, J Xu, W Liang, J Li, L Feng, PX Zheng… - International Journal of …, 2019 - hindawi.com
… Common variation of HMGA2 gene can greatly enhance nephropathy of type 2 diabetic patients
… In our research, it was displayed that HMGA2 was a target of miR-98-5p. We proved that …
… In our research, it was displayed that HMGA2 was a target of miR-98-5p. We proved that …
Long non-cording RNA XIST promoted cell proliferation and suppressed apoptosis by miR-423-5p/HMGA2 axis in diabetic nephropathy
H Chen, Y Guo, X Cheng - Molecular and Cellular Biochemistry, 2021 - Springer
… of DN included genetic susceptibility DN gene, increasing … Common genetic variants (single-nucleotide
polymorphisms, … roles in the progression of type 2 diabetes and non-alcoholic …
polymorphisms, … roles in the progression of type 2 diabetes and non-alcoholic …
The genetic map of diabetic nephropathy: evidence from a systematic review and meta-analysis of genetic association studies
… Although many genetic variants have been implicated in DN susceptibility, the results are …
The diabetes could be either Type I diabetes mellitus (T1DM) or Type II diabetes mellitus (…
The diabetes could be either Type I diabetes mellitus (T1DM) or Type II diabetes mellitus (…
[PDF][PDF] Serum circulating microRNA profiling for identification of potential markers of diabetic nephropathy in black African South Africans with type 2 diabetes mellitus
MSD Valentin - 2020 - wiredspace.wits.ac.za
… HMGA2 gene, that has been implicated in activation of the TGF-β1 signalling pathway. Thus,
increased … factors for T2DM have been linked to susceptibility to and development of insulin …
increased … factors for T2DM have been linked to susceptibility to and development of insulin …
[HTML][HTML] The genetics of diabetic nephropathy
… There is evidence for a genetic susceptibility to nephropathy … and the transcription factor
HMGA2. Interestingly, treatment of … genetic variants associated with diabetic kidney disease will …
HMGA2. Interestingly, treatment of … genetic variants associated with diabetic kidney disease will …
[HTML][HTML] Identified single-nucleotide polymorphisms and haplotypes at 16q22. 1 increase diabetic nephropathy risk in Han Chinese population
… BMP4 and BMP7 genes did not strongly influence genetic susceptibility to DN [… two SNPs
in BMP7 gene may be susceptibility variants of DN in Han Chinese patients with type 2 diabetes…
in BMP7 gene may be susceptibility variants of DN in Han Chinese patients with type 2 diabetes…
[HTML][HTML] A genome-wide association study for diabetic nephropathy genes in African Americans
CW McDonough, ND Palmer, PJ Hicks, BH Roh… - Kidney international, 2011 - Elsevier
… Thus, our results suggest that multiple loci underlie susceptibility to kidney disease in … near
two coding genes: HMGA2, high mobility group AT-hook 2 (101 kb upstream of the variant), …
two coding genes: HMGA2, high mobility group AT-hook 2 (101 kb upstream of the variant), …
A potentially functional polymorphism in the regulatory region of let-7a-2 is associated with an increased risk for diabetic nephropathy
J Zhou, R Peng, T Li, X Luo, H Peng, H Zha, P Yin… - Gene, 2013 - Elsevier
… variant rs1143770 was significantly associated with the … candidate microRNA involving in
the susceptibility to DN. … A total of 212 patients were enrolled in this study with type 2 diabetes …
the susceptibility to DN. … A total of 212 patients were enrolled in this study with type 2 diabetes …