… of a sulphydryl group which is not present in other ACE inhibitor drugs. We have compared
the effects of captopril and enalapril on free radical activity in thirty-two diabetic subjects with …

… Some studies have focused on their in vitro antioxidant … Diabetes has been associated with
increased free radical … peroxidase activities are increased by enalapril and captopril in mouse …

… In vitro and in vivo antioxidant and antihypertensive potential … Captopril (d-3-mercapto2-methylpranory-l-proline),
enalapril, and … and stable for at least 3 months under refrigeration (2–6 …

… We hypothesized that both ACE inhibitor (ACEI) and … portion of FDD inhibited by oxygen
free radicals. EC-SOD … of NO in vivo, we determined the effect of the antioxidant vitamin C on …

… 12 A free radical scavenger action has also been postulated. … treatment with enalapril or
captopril increases enzymatic and … -GPx inactivation (Fig 1C), as was suggested to occur in vitro. …

… treatment, concomitant diseases, diabetes mellitus and chronic renal … action of captopril as
an ACE inhibitor and a free radical scavenger has been repeatedly reported in in vitro studies […

… injury in vivo [ 191. In rats that were made hypertensive by infusion with angiotensin II, free
radical … In our study, both captopril and enalapril substantially inhibited the oxidation of the …

… of hEW on the in vivo antioxidant status in plasma and several … support the free radical-scavenging
activity of captopril, … However, neither captopril nor the ACE-inhibitor peptide Met-…

… In vitro studies in which the photooxidation of riboflavin … remarkable difference in the antioxidant
action of ACE inhibitors with or … by captopril linked with its free radical scavenging action. …

… (1991) Comparison of the free radical scavenging activity of captopril versus enalapril: A
three-month in vivo study in hypertensive diabetic patients. J. Hum. …