Competing oscillators in cardiac pacemaking: historical background
D Noble, PJ Noble, M Fink - Circulation research, 2010 - Am Heart Assoc
… Those historical results fully support the synthesis proposed in the articles in this review
series. The oscillator mechanisms do not primarily compete with each; they entrain each other. …
series. The oscillator mechanisms do not primarily compete with each; they entrain each other. …
[HTML][HTML] From two competing oscillators to one coupled-clock pacemaker cell system
Y Yaniv, EG Lakatta, VA Maltsev - Frontiers in physiology, 2015 - frontiersin.org
… uptake and release forming additional oscillator mechanism in pacemaker cells, termed Ca
2… concept that coupled-clock pacemaker system controls the cardiac pacemaker cell function. …
2… concept that coupled-clock pacemaker system controls the cardiac pacemaker cell function. …
To beat or not to beat: the history and development of heart pacemakers
DJ Woollons - Engineering Science & Education Journal, 1995 - IET
… It measured 6 cm in diameter by 15 cm thick and contained a blocking oscillator generating
a … In the VAT mode a possibility of competition exists between the ventricular pacing resulting …
a … In the VAT mode a possibility of competition exists between the ventricular pacing resulting …
[HTML][HTML] Mathematical models of cardiac pacemaking function
… these independent pacemaking oscillators in the heart are assigned … of cardiac pacemaking
activity has historically been under … In this review, we have presented these hypotheses and …
activity has historically been under … In this review, we have presented these hypotheses and …
Are physiological oscillations physiological?
L Xiong, A Garfinkel - The Journal of Physiology, 2023 - Wiley Online Library
… sinoatrial node (SAN), the heart’s natural pacemaker, there are at least two oscillatory … ,
generating rhythmic pacemaking.’ Whether the origin of the cellular oscillation is subcellular or …
generating rhythmic pacemaking.’ Whether the origin of the cellular oscillation is subcellular or …
Modern perspectives on numerical modeling of cardiac pacemaker cell
… evolution of pacemaker mechanisms (4), this critical review discusses only those limited
historical aspects … In their recent article “Competing oscillators in cardiac pacemaking: historical …
historical aspects … In their recent article “Competing oscillators in cardiac pacemaking: historical …
Historical highlights in cardiac pacing
LA Geddes - IEEE Engineering in Medicine and Biology …, 1990 - ieeexplore.ieee.org
… 9b) consisted of a transistor oscillator and an amplifier energized by 10 mercuryzinc cells. …
it solves the competitive pacing problem. Early in the development of pacemakers, various …
it solves the competitive pacing problem. Early in the development of pacemakers, various …
[PDF][PDF] Mechanisms underlying cardiac pacemaker activity
M Vassalle - JOURNAL OF MEDICAL SCIENCES-TAIPEI, 2003 - researchgate.net
… This conclusion is strengthened by the fact that the pacemaker current (I,,,) reverses past the
… this prevents Purkinje fibers from competing with SAN under normal circumstances, a safety …
… this prevents Purkinje fibers from competing with SAN under normal circumstances, a safety …
[HTML][HTML] The cardiac pacemaker story—fundamental role of the Na+/Ca2+ exchanger in spontaneous automaticity
… Few areas of cardiac cellular electrophysiology had more intense debate over the years …
In the last two decades, we could witness the struggle of two competing oscillator concepts …
In the last two decades, we could witness the struggle of two competing oscillator concepts …
Pacemaking in cardiac tissue. From IK2 to a coupled‐clock system
E Carmeliet - Physiological Reports, 2019 - Wiley Online Library
… (2010) in “Competing oscillators in cardiac pacemaking”: “… 2016), I mentioned some personal
historical notes. Afterwards, … a more substantial review on the historical evolution of cardiac …
historical notes. Afterwards, … a more substantial review on the historical evolution of cardiac …