… direct identification of obesity genes. In … mouse models regarding genetics of complex
obesity. First, we summarize increasingly powerful ways to harness the strength of mouse models …

… have been produced that influence individual components of obesity. This article provides …
of genetic factors influencing the most widely distributed patterns of complex obesity. Glossary …

Insights into the etiology of human obesity have arisen from the study of animal models. Animal
models of obesity are also important for the development of future treatments of obesity. …

… models of genetic obesity exist in rodents. Over the past few years, the methodology of
molecular genetics … recently been applied to complex mouse models of obesity. There are some …

… This condition results from a constant and complex interplay between … obesity relied heavily
on mouse genetic studies. By searching the available literature on mouse models of obesity, …

… However, the regulation of energy balance is an extremely complex … occurring monogenic
and polygenic obese mouse strains, as … In this review, mouse models of obesity or leanness …

… unprecedented resolution for mapping complex traits. In addition, we describe recent
advancements in applying mouse models to begin to dissect genetic predisposition to previously …

… higher estimates of heritability in obesity than more complex studies of other relatives? …
Hypothalamic and genetic obesity in experimental animals. Physiol Rev 1979; 59: 719ą809. …

… genetics of obesity. At present, the mapping of loci contributing to complex traits in animal
models … method for identifying new genetic factors contributing to obesity and its associated …

… can be difficult to separate from genetic effects. This is one area where an obesity-related …
in humans rather than in animal models, but in spite of this, animal models provide a very …