… falciparum isolates from Nigeria, Malawi or Senegal. This study reports for the first time
cytb Tyr268Asn mutation in unexposed P. falciparum isolates from Nigeria. The …

… vitro susceptibility testing or confirm adequate blood levels of … rate of development of
atovaquone resistance during AP … including large swaths of Sub-Saharan Africa [40]. Due to the …

… phenotyping or genotyping among 477 unexposed African P. … ), before the emergence of
atovaquone/proguanil resistance, … confirmation of atovaquone-proguanil-resistant Plasmodium …

… in the cytochrome b gene has been described [3] and confirmed in … Africa (Ethiopia and
Gabon) where atovaquone/proguanil … the emergence of resistance against atovaquone/proguanil …

… the samples was sequenced to confirm PCR-RFLP results using … of isolates from Africa,
one sample carrying Y268S, isolated … Plasmodium falciparum malaria with atovaquone-proguanil …

… However, pfcyt-b mutations have been found among African parasite isolates without a history
of … failures have been confirmed as carrying parasites with pfcyt-b mutations, suggesting a …

… by multiple mutations in the Plasmodium falciparum dihydrofolate … confirmation of
atovaquone–proguanil resistance in P. … to identify emergence and to monitor the spread of …

… The emergence of Plasmodium falciparum resistant to most … Thai isolates was apparently
higher than African isolates [15, … analysis also confirmed that all selected 20 isolates had a wild…

… The atovaquone-proguanil (AP) drug combination, is one of the … Plasmodium falciparum
in vitro resistance to ATQ has been … In order to confirm whether an heritable genetic mutation …

… of mutations associated with most atovaquone-proguanil … Along with the key issue of
emergence and spreading of … three ratio reported for 135 isolates from West and Central Africa …