… , is sufficient to transform cells. Here we demonstrate that constitutive activation of the CD40
pathway by a chimeric LMP1CD40 molecule resembles the transforming function of LMP1 in …

… expression of CD40-like, latent membrane protein 1 (LMP1) … in the lymphoid tissues, LMP1
acts constitutively, in a ligand … signals that could participate in this important process in vivo. …

… (EBF1) to promote transformation of LMP1-expressing B cells by … EBV EBNA3A phenocopies
EBF1 activities in LMP1-… LMP1 constitutively activates the IKK signaling cascade, while Rel …

… The mimicry of CD40 signaling by LMP1 has been … these 2 signals are provided constitutively
by LMP2A and LMP1 … G: Constitutive CD40 signaling phenocopies the transforming func…

… Epstein Barr virus latent membrane protein 1 (LMP1) induces … LMP1 constitutively activates
NF-κB through two domains in … of LMP1 are not sufficient to initiate signaling through CD40 in …

… , and the viral oncoprotein latent membrane protein 1 (LMP1) … Not unexpectedly considering
LMP1 is a constitutively … TRAF molecules and LMP1 can partially substitute for CD40 loss in …

… and LMP1 have been shown to be essential for the in-vitro … , which, when depleted, partially
phenocopied EBNA1 depletion by … LMP1 has many functional similarities to a constitutively …

… Epstein Barr virus latent membrane protein 1 (LMP1) plays … signalling of the human TNF
receptor family member CD40 in EBV… While in vitro LMP1 expression is controlled by the EBNA2 …

… expression of Epstein–Barr nuclear antigen 2 (EBNA2) and LMP1, considered … Constitutive
CD40 signaling phenocopies the transforming function of the EBV oncoprotein LMP1 in vitro …

… of immortalization and growth-transformation of B cells infected in vitro. The work … LMP1
and LMP2A are viral homologues of CD40 and BCR, respectively. LMP1 signals constitutively …