… Altered kinetics of the photoresponse from retinas of mice heterozygous for the retinal … levels
of cyclic nucleotides in retinas of mice heterozygous for a gene for photoreceptor dystrophy. …

… conversion of a the early onset photoreceptor dysplasia category. … heterozygous setter retina
demonstrates normal cyclic GMP … for a gene for photoreceptor dystrophy. Biochem. Biophys. …

… that cyclic GMP plays in the degenerating of RCS photoreceptors … particularly the early-onset
form of inherited retinal degeneration. … retinal dystrophy in the rat. J. Cell Biol., 49, 664-682. …

… adapted retinas from normal mice (++/++) and from mice heterozygous for the photoreceptor
dystrophy gene (rdle/++)… In light adapted retinas cyclic GMP levels were 40% lower in the …

… concentrations typical for dark-adapted rods. The transgenic mice demonstrated early-onset …
model for exploring cellular mechanisms of the CORD6-related photoreceptor death. This …

… P873R) cause either adCRD or are found in a heterozygous state in an isolated case with
… Four individuals of the MOL0064 family participated in this study, showing early onset retinal …

… The rise in photoreceptor cGMP, induced by c l.OnM extracellular calcium, is delayed in
retinas of mice heterozygous for the rod dysplasia gene (+lrd). The calcium ionophore A23187 …

… in the heterozygous control retinas (309 pmoles mg-' min-I). … that the high cyclicGMP levels
in photoreceptor cell dysplasia could … Inherited retinal dystrophy: Primary defect in pigment …

… the use of the term early onset severe retinal dystrophy (EOSRD) to … in the heterozygous
state with a more typical GC1 null … However, the photoreceptors in these mice degenerated, and …

… Guanylate cyclases (GCs) synthesize cyclic GMP (cGMP), a … In addition, heterozygous
NPR2 mutations were found to be … an autosomal recessive, early onset dystrophy defined as a “…