D-cycloserine, a putative cognitive enhancer, facilitates activation of the N-methyl-D-aspartate receptor-ionophore complex in Alzheimer brain

IP Chessell, AW Procter, PT Francis, DM Bowen - Brain Research, 1991 - Elsevier
… the known involvement of the receptor complex in long-term potentiation and … brain tissue
obtained very shortly after death to determine the action of DCS at the NMDA receptor complex

[HTML][HTML] Involvement of cholinergic, adrenergic, and glutamatergic network modulation with cognitive dysfunction in Alzheimer's disease

YJ Cheng, CH Lin, HY Lane - International Journal of Molecular Sciences, 2021 - mdpi.com
… We also discuss the key role of N-methyl-d-aspartate receptor (… In the brains of patients
with Alzheimer-type dementia, the … d-cycloserine can facilitate NMDAR–ionophore complex

NMDA neurotransmission dysfunction in mild cognitive impairment and Alzheimer's disease

CH Lin, YJ Huang, CJ Lin, HY Lane… - Current pharmaceutical …, 2014 - ingentaconnect.com
… that mediated by the N-methyl-D-aspartate (NMDA) receptor, … to facilitate the activation of
the NMDAR complex in the brain … daily; in this study, D-cycloserine did not show any efficacy in …

Improved cognition in Alzheimer's disease with short-term D-cycloserine treatment

GE Tsai, WE Falk, J Gunther… - American journal of …, 1999 - Am Psychiatric Assoc
… of N-methyl-d-aspartate subtype glutamate receptor, facilitating activation of the receptor and
improving cognition and … of NMDA receptors isolated from the brains of Alzheimer’s disease …

Ultimate translation: developing therapeutics targeting on N-methyl-d-aspartate receptor

GE Tsai - Advances in Pharmacology, 2016 - Elsevier
… , aging, mild cognitive impairment and Alzheimer's dementia, … has no specific transporter
across the blood–brain barrier. … , and the magnitude of d-cycloserine-facilitated virtual reality …

A review of the actions of d-cycloserine, a putative nootropic agent, at the NMDA receptor complex-associated glycine binding site

JW Allen - McGill Journal of Medicine, 1996 - mjm.mcgill.ca
… such as Alzheimer's disease. Following the discovery of the … the N-methyl-D-aspartate
receptor ionophore complex in rat … glycine receptor with D-cycloserine facilitates learning and …

D-cycloserine treatment of Alzheimer disease

C Randolph, JW Roberts, MC Tierney… - Alzheimer Disease & …, 1994 - journals.lww.com
… partial indirect agonist at certain N-methylD-aspartate (NMDA) … learning facilitated by a
monoclonal antibody or d-cycloserine… enzyme-activated inhibitor of brain monoamine oxidase B. J …

Effects of D-cycloserine and aniracetam on spatial learning in rats with entorhinal cortex lesions

W Zajaczkowski, W Danysz - Pharmacology Biochemistry and Behavior, 1997 - Elsevier
… vitro potency of d-cycloserine at NMDA receptors and in vivo brain … may be not suitable
the for therapy of Alzheimer's disease where … Actions of d-cycloserine at the N-methyl-D-aspartate-…

Treatment of Alzheimer's disease.

DM Bowen, PT Francis, AW Procter… - Journal of Neurology …, 1992 - ncbi.nlm.nih.gov
… Characterisation of the glycine modulatory site of the N-methyl-D-aspartate receptor
ionophore complex in human brain. … D-cycloserine, a putative cognitive enhancer, facilitates

Reversion of β25–35-amyloid peptide-induced amnesia by NMDA receptor-associated glycine site agonists

T Maurice, BP Lockhart, TP Su, A Privat - Brain research, 1996 - Elsevier
… , DM, D-Cycloserine, a putative cognitive enhancer, facilitates activation of the N-methyl-D-aspartate
receptor-ionophore complex in Alzheimer brain, Brain Res., 565 (1991) 345-348. [3] …