… genotypes of Plasmodium falciparum isolates from Gabon correlate with in vitro activity of pyrimethamine and cycloguanil, but not with sulfadoxine–pyrimethamine …
…, M Bakary, J Le Bras, P Deloron - Journal of …, 2003 - academic.oup.com
… in this article are part of a treatment efficacy study that compared the sulfadoxine–pyrimethamine
(SP) … Unfortunately, our isolates did not include a genotype mutant at both 436 and 437 …
(SP) … Unfortunately, our isolates did not include a genotype mutant at both 436 and 437 …
[HTML][HTML] High prevalence of genotypes associated with sulfadoxine/pyrimethamine resistance in the rural area of Fougamou, Gabon
FM Boukoumba, JB Lekana-Douki, PB Matsiegui… - Journal of Global …, 2021 - Elsevier
… Plasmodium falciparum dihydropteroate synthase (Pfdhps) and … Clinical trials to investigate
the efficacy of IPT-SP are much … Pyrimethamine binds far more strongly to the parasite DHFR …
the efficacy of IPT-SP are much … Pyrimethamine binds far more strongly to the parasite DHFR …
[HTML][HTML] High prevalence of dhfr triple mutant and correlation with high rates of sulphadoxine-pyrimethamine treatment failures in vivo in Gabonese children
G Mombo-Ngoma, S Oyakhirome, R Ord, JJ Gabor… - Malaria Journal, 2011 - Springer
… -108, which is associated with cycloguanil resistance [28–30]. … of SP treatment efficacy in
Gabon. These findings suggest … Treatment during infancy with sulfadoxine-pyrimethamine (…
Gabon. These findings suggest … Treatment during infancy with sulfadoxine-pyrimethamine (…
[HTML][HTML] Polymorphism in dhfr/dhps genes, parasite density and ex vivo response to pyrimethamine in Plasmodium falciparum malaria parasites in Thies, Senegal
D Ndiaye, B Dieye, YD Ndiaye, D Van Tyne… - International Journal for …, 2013 - Elsevier
… be incorporated with ongoing in vivo efficacy monitoring in areas … falciparum isolates
from Thies, as the increase in the number … Dhfr and dhps genotype and sulfadoxine–pyrimethamine …
from Thies, as the increase in the number … Dhfr and dhps genotype and sulfadoxine–pyrimethamine …
… of quintuple mutant dhps/dhfr genes in Plasmodium falciparum infections seven years after introduction of sulfadoxine and pyrimethamine as first line treatment in …
B Bwijo, A Kaneko, M Takechi, IL Zungu, Y Moriyama… - Acta tropica, 2003 - Elsevier
… and sulfadoxine/pyrimethamine activity against parasite … To evaluate SP efficacy seven
years after Malawi replaced … between pyrimethamine and cycloguanil activity in vitro and …
years after Malawi replaced … between pyrimethamine and cycloguanil activity in vitro and …
[PDF][PDF] Polymorphisms in pfcrt, pfmdr1, dhfr genes and in vitro responses to antimalarials in Plasmodium falciparum isolates from Bangui, Central African Republic
D Menard, F Yapou, A Manirakiza… - … American journal of …, 2006 - publicationslist.org
… genotype and chemosensitivity to pyrimethamine. For the … associated with sulfadoxine-pyrimethamine
(SP) treatment failure … vitro susceptibility of Gabonese wild isolates of Plasmodium …
(SP) treatment failure … vitro susceptibility of Gabonese wild isolates of Plasmodium …
[HTML][HTML] … allele Pfdhps 437G and Pfdhfr triple mutation in Plasmodium falciparum isolates from a rural area of Gabon, three years after the change of malaria treatment …
JM Ndong Ngomo, DP Mawili-Mboumba… - … and treatment, 2016 - hindawi.com
… with in vitro activity of pyrimethamine and cycloguanil, but not with sulfadoxine-pyrimethamine
treatment efficacy,” … falciparum: genotyping of dihydrofolate reductase and dihydropteroate …
treatment efficacy,” … falciparum: genotyping of dihydrofolate reductase and dihydropteroate …
Prevalence of Plasmodium falciparum antimalarial drug resistance genes in Southeastern Gabon from 2011 to 2014
DF Voumbo-Matoumona, LC Kouna… - Infection and drug …, 2018 - Taylor & Francis
… mutants that were associated with pyrimethamine resistance … three localities suggests the
efficiency of SP as IPTp. Citation62 This … treatment with sulfadoxine/pyrimethamine in Gabon. J …
efficiency of SP as IPTp. Citation62 This … treatment with sulfadoxine/pyrimethamine in Gabon. J …
Prevalence of Plasmodium falciparum parasites resistant to sulfadoxine/pyrimethamine in pregnant women in Yaoundé, Cameroon: emergence of highly resistant …
P Chauvin, S Menard, X Iriart… - Journal of …, 2015 - academic.oup.com
… (IPTp-SP) efficacy is highly detrimental. The second … resistance to pyrimethamine and
sulfadoxine in vitro and in vivo, … neighbouring Cameroon was 6.25% in Gabon in 2007, 27 0.8% in …
sulfadoxine in vitro and in vivo, … neighbouring Cameroon was 6.25% in Gabon in 2007, 27 0.8% in …
[HTML][HTML] Molecular markers of resistance to amodiaquine plus sulfadoxine–pyrimethamine in an area with seasonal malaria chemoprevention in south central Niger
RF Grais, IM Laminou, L Woi-Messe, R Makarimi… - Malaria journal, 2018 - Springer
… with resistance to pyrimethamine and pfdhps 436A/F/H and … /S, associated with resistance
to cycloguanil [18] and mutation … with genotypes known to compromise SP efficacy in Gabi are…
to cycloguanil [18] and mutation … with genotypes known to compromise SP efficacy in Gabi are…