[HTML][HTML] Defining Emerging Roles for NF-κB in Antivirus Responses: Revisiting the Interferon-β Enhanceosome Paradigm
S Balachandran, AA Beg - PLoS pathogens, 2011 - journals.plos.org
… of NF-κB's overall function in the innate antivirus response, in which NF-κB has a crucial
constitutive (and early) role in … and potentially more general later role in regulating expression of …
constitutive (and early) role in … and potentially more general later role in regulating expression of …
[HTML][HTML] Nei-like DNA glycosylase 2 selectively antagonizes interferon-β expression upon respiratory syncytial virus infection
… Our results show that NEIL2 antagonizes nuclear factor κB (NF-κB) … genome fidelity but also
for controlling immune responses. … that the role of NEIL2 is significant in the early response of …
for controlling immune responses. … that the role of NEIL2 is significant in the early response of …
The role of viral hemorrhagic septicemia virus (VHSV) NV gene in TNF-α-and VHSV infection-mediated NF-κB activation
… Therefore, it can be considered that (i) suppression of NF-κB activity by VHSV may influence
on the type I interferon response through down-regulation of interferon-β enhanceosome …
on the type I interferon response through down-regulation of interferon-β enhanceosome …
Differential requirement for the IKKβ/NF-κB signaling module in regulating TLR-versus RLR-induced type 1 IFN expression in dendritic cells
X Wang, J Wang, H Zheng, M Xie… - The Journal of …, 2014 - journals.aai.org
… for the host antivirus response. To determine the potential role of the IKKβ/NF-κB pathway in
virus-… play a key role in determining specificity of host responses against different infectious …
virus-… play a key role in determining specificity of host responses against different infectious …
[HTML][HTML] NF-κB and IRF pathways: cross-regulation on target genes promoter level
M Iwanaszko, M Kimmel - BMC genomics, 2015 - Springer
… NF-κB and IRF pathways may be crucial for determining the … NF-κB-deficient cells has
shown that the initial kinetics of the type I interferon (IFN) response depends on concurrent NF-κB …
shown that the initial kinetics of the type I interferon (IFN) response depends on concurrent NF-κB …
Zebrafish NF-κB/p65 is required for antiviral responses
G Ouyang, Q Liao, D Zhang, F Rong, X Cai… - The Journal of …, 2020 - journals.aai.org
… the NF-κB family are essential for the inflammatory response as well as for innate and adaptive
immunity. NF-κB … The canonical NF-κB pathway responds to diverse immune stimulations …
immunity. NF-κB … The canonical NF-κB pathway responds to diverse immune stimulations …
[HTML][HTML] Of Keeping and Tipping the Balance: Host Regulation and Viral Modulation of IRF3-Dependent IFNB1 Expression
H Schwanke, M Stempel, MM Brinkmann - Viruses, 2020 - mdpi.com
… response we will briefly revisit below (see Section 3.3), wherein only a part of the IFNB1
alleles are engaged in the early response… of NF-κB is the most limiting factor of enhanceosome …
alleles are engaged in the early response… of NF-κB is the most limiting factor of enhanceosome …
[HTML][HTML] Autophagy diminishes the early interferon-β response to influenza A virus resulting in differential expression of interferon-stimulated genes
BP Perot, J Boussier, N Yatim, JS Rossman… - Cell Death & …, 2018 - nature.com
… relies on nuclear factor-kappaB (NF-κB) activation 50 . To … NF-κB activation through IκBα
degradation and NF-κB reporter assay, observing that autophagy limited IAV-induced NF-κB …
degradation and NF-κB reporter assay, observing that autophagy limited IAV-induced NF-κB …
[HTML][HTML] Enhanceosome transcription factors preferentially dimerize with high mobility group proteins
… is an enhancer located upstream of the human interferon β gene, bound by … response to
stimulation with bacterial lipopolysaccharide (LPS). This study also identified a cluster of NF- κB …
stimulation with bacterial lipopolysaccharide (LPS). This study also identified a cluster of NF- κB …
[HTML][HTML] Dynamic cross talk model of the epithelial innate immune response to double-stranded RNA stimulation: coordinated dynamics emerging from cell-level noise
R Bertolusso, B Tian, Y Zhao, L Vergara, A Sabree… - PloS one, 2014 - journals.plos.org
… the NF-κB and IRF3 signaling arms is critical for determining … Although NF-κB is a component
of the enhanceosome, IFNβ … the absence of NF-κB, the rapid response of IFNβ expression …
of the enhanceosome, IFNβ … the absence of NF-κB, the rapid response of IFNβ expression …