[HTML][HTML] Defining Emerging Roles for NF-κB in Antivirus Responses: Revisiting the Interferon-β Enhanceosome Paradigm

S Balachandran, AA Beg - PLoS pathogens, 2011 - journals.plos.org
… of NF-κB's overall function in the innate antivirus response, in which NF-κB has a crucial
constitutive (and early) role in … and potentially more general later role in regulating expression of …

[HTML][HTML] Nei-like DNA glycosylase 2 selectively antagonizes interferon-β expression upon respiratory syncytial virus infection

L Pan, Y Xue, K Wang, X Zheng, A Islam… - Journal of Biological …, 2023 - ASBMB
… Our results show that NEIL2 antagonizes nuclear factor κB (NF-κB) … genome fidelity but also
for controlling immune responses. … that the role of NEIL2 is significant in the early response of …

The role of viral hemorrhagic septicemia virus (VHSV) NV gene in TNF-α-and VHSV infection-mediated NF-κB activation

MS Kim, KH Kim - Fish & shellfish immunology, 2013 - Elsevier
… Therefore, it can be considered that (i) suppression of NF-κB activity by VHSV may influence
on the type I interferon response through down-regulation of interferon-β enhanceosome

Differential requirement for the IKKβ/NF-κB signaling module in regulating TLR-versus RLR-induced type 1 IFN expression in dendritic cells

X Wang, J Wang, H Zheng, M Xie… - The Journal of …, 2014 - journals.aai.org
… for the host antivirus response. To determine the potential role of the IKKβ/NF-κB pathway in
virus-… play a key role in determining specificity of host responses against different infectious …

[HTML][HTML] NF-κB and IRF pathways: cross-regulation on target genes promoter level

M Iwanaszko, M Kimmel - BMC genomics, 2015 - Springer
NF-κB and IRF pathways may be crucial for determining the … NF-κB-deficient cells has
shown that the initial kinetics of the type I interferon (IFN) response depends on concurrent NF-κB

Zebrafish NF-κB/p65 is required for antiviral responses

G Ouyang, Q Liao, D Zhang, F Rong, X Cai… - The Journal of …, 2020 - journals.aai.org
… the NF-κB family are essential for the inflammatory response as well as for innate and adaptive
immunity. NF-κB … The canonical NF-κB pathway responds to diverse immune stimulations …

[HTML][HTML] Of Keeping and Tipping the Balance: Host Regulation and Viral Modulation of IRF3-Dependent IFNB1 Expression

H Schwanke, M Stempel, MM Brinkmann - Viruses, 2020 - mdpi.com
response we will briefly revisit below (see Section 3.3), wherein only a part of the IFNB1
alleles are engaged in the early response… of NF-κB is the most limiting factor of enhanceosome

[HTML][HTML] Autophagy diminishes the early interferon-β response to influenza A virus resulting in differential expression of interferon-stimulated genes

BP Perot, J Boussier, N Yatim, JS Rossman… - Cell Death & …, 2018 - nature.com
… relies on nuclear factor-kappaB (NF-κB) activation 50 . To … NF-κB activation through IκBα
degradation and NF-κB reporter assay, observing that autophagy limited IAV-induced NF-κB

[HTML][HTML] Enhanceosome transcription factors preferentially dimerize with high mobility group proteins

A Jankowski, P Obara, U Mathur, J Tiuryn - BMC Systems Biology, 2015 - Springer
… is an enhancer located upstream of the human interferon β gene, bound by … response to
stimulation with bacterial lipopolysaccharide (LPS). This study also identified a cluster of NF- κB

[HTML][HTML] Dynamic cross talk model of the epithelial innate immune response to double-stranded RNA stimulation: coordinated dynamics emerging from cell-level noise

R Bertolusso, B Tian, Y Zhao, L Vergara, A Sabree… - PloS one, 2014 - journals.plos.org
… the NF-κB and IRF3 signaling arms is critical for determining … Although NF-κB is a component
of the enhanceosome, IFNβ … the absence of NF-κB, the rapid response of IFNβ expression …