Deiodinase activities in thyroids and tissues of iodine-deficient female rats

R Lavado-Autric, RM Calvo, RM de Mena… - …, 2013 - academic.oup.com
… plasma TSH. We studied changes in deiodinase activities and mRNA in several tissues of
rats … T 4 and T 3 concentrations decreased in plasma, tissues, and thyroids of LID rats, and T 4 …

Expression of iodotyrosine deiodinase in thyroid and other organs in iodine-deficient and iodine-excess rats

X Sun, X Zhang, Y Jiang, S Bao, Z Shan… - Biological trace element …, 2015 - Springer
… was kept in paraformaldehyde, whereas the other part of the thyroid and tissues (liver and
… , T4, and activity of iodothyronine deiodinase in liver of iodine deficient rats were decreased …

The effects of iodine deficiency on thyroid hormone deiodination

MJ Obregon, FE del Rey, GM de Escobar - Thyroid, 2005 - liebertpub.com
… severely iodine-deficient adult rats, other tissues considered … (49) and functionally hypothyroid,
despite circulating T3 that … and activity in different regions of the iodine-deficient rat brain …

Effects of selenium and iodine deficiency on type I, type II and type III iodothyronine deiodinases and circulating thyroid hormones in the rat

H Meinhold, A Campos-Barros… - Experimental and …, 1993 - thieme-connect.com
… considerably in our severely hypothyroxinemic iodine-deficient rats despite euthyroid serum
T3 levels. … and cold exposure on thyroxine 5'-deiodinase activity in various rat tissues. Am. J. …

Mechanisms of adaptation to iodine deficiency in rats: thyroid status is tissue specific. Its relevance for man

PE Pedraza, MJ Obregon, HF Escobar-Morreale… - …, 2006 - academic.oup.com
… in all groups, including the severely iodine-deficient LID′ animals that had a decreased …
the activities of the iodothyronine deiodinase isoenzymes in most tissues or activities of other …

Iodothyronine deiodinase activities in fetal rat tissues at several levels of iodine deficiency: a role for the skin in 3, 5, 3′-triiodothyronine economy?

JP Schröder-van der Elst, D van der Heide… - …, 1998 - academic.oup.com
… Their activity is dependent on the thyroid (hormone) and nutritional status and is … activity
in liver decreased (6). Most of these studies were performed with severely iodine-deficient rats, …

Outer ring iodothyronine deiodinases and thyroid hormone economy: responses to iodine deficiency in the rat fetus and neonate

MJ Obregón, CR DE OÑA, R CALVO… - …, 1991 - academic.oup.com
… of T3 to this tissue. In summary, both fetuses and suckling pups from iodine-deficient
mothers are … on thyroxine 5'-deiodinase activity in various rat tissues Am J Physiol 26O:E175-E182 …

Effect of iodine supplement on iodine status and 5′-deiodinase activity in the brain of neonatal rats with iodine deficiency

N Liu, A Zuo, D Liang, Z Zhang, G Guo… - Biological trace element …, 2006 - Springer
… are 720 million people living in an iodinedeficient environment in China. … of thyroid status on
the activities of 5′- and 5-deiodinases … T4 per hour per gram tissue (ng T3/µg T4/h/g tissue). …

Defining the roles of the iodothyronine deiodinases: current concepts and challenges

DL St. Germain, VA Galton, A Hernandez - Endocrinology, 2009 - academic.oup.com
… 5′-deiodination in the thyroid and in extrathyroidal tissues … T 3 production in the euthyroid
neonatal rat (58, 119), and 3) … learn to manipulate local deiodinase activity and TH action in …

Regulation of type 1 iodothyronine deiodinase in health and disease

RJ Koenig - Thyroid, 2005 - liebertpub.com
… in numerous other tissues, such as (in the rat) intestine, … 5!-deiodinase activity is modified in
rats under restricted feeding … indiscriminate supplementation of iodine-deficient subjects with …