… In this study, a novel class of hybrid thiazole-based flavanoid derivatives were synthesized
… for antibacterial activity for possible benefit in bone trauma via inhibition of DNA gyrase …

… -flavanoid showed considerable inhibition of DNA gyrase. … antimicrobial activity of a series
of eight thiazole-based two … effects by evaluating the acute phase bone marrow response, …

… The methodology offered advantages such as mild reaction … inhibitory concentration
against four distinct bacterial strains. … Pharmaceutical drug development increasingly relies on …

… The authors did not report the antimicrobial action of luteolin. Docking analysis was also
applied to develop new thiazole-based flavanoids able to inhibit DNA gyrase [48]. …

… the antimicrobial thiazole-based hybrid compounds from the … ATP binding domain of bacterial
DNA gyrase B and the fungal … Flavones are part of the large family of flavonoids, a widely …

… the antimicrobial thiazole-based hybrid compounds from the … ATP binding domain of bacterial
DNA gyrase B and the fungal … Design and development of some thiazole-based flavanoids …

… For instance, the gyrase gene present in bacterial membranes … in this organism for different
categories of antibiotics. In addition … The pathogen also causes infections affecting bones and …

… a panel of reference strains of nineteen microorganisms from … The inhibition of microbial
growth was judged by comparison … Their antimicrobial effect was similar and even stronger to …

… caused by ESKAPE pathogens and other antibiotic-resistant … that act as precursors for
flavonoids. They are commonly seen in … designed and synthesized to act as efficient DNA gyrase …

… used as antimicrobial agent for curing the animal injuries and … is the most important model
organism whose biology and … activity of the flavonoids and saponins yielded from the active n…