… technique starting from wet nano-milling, named “dry nanosuspension” technique for
poorly water-soluble drugs. The spray freeze-drying (SFD) method was applied instead of the …

… spray freeze-drying (SFD) method combined with wet-milling … the milled nanosuspension
dropwise from a nozzle tip into liquid … tool improving the solubility of poorly water-soluble drugs. …

… spray-freeze drying of drug nanosuspensions was suggested as a novel dissolution-enhancing
technique for poorly water-soluble drugs… of the concept of quality by design [Citation96]. …

… of drug nanocrystals, with an emphasis on wet milling, while … Freeze drying of drug
nanosuspensions prepared via LASP … nanocomposite particles by freeze drying and spray drying. …

… with Tween 80® were designed by wet milling. A full factorial … with different cryoprotectants
was carried out to obtain a dry … the nanocrystals as a nanosuspension and would be slowed …

… using ketoconazole as a poorly water-soluble model drug. By the means of a design of …
is only caused by the freeze-drying phase as the nanosuspensions were physically stable …

… original and redispersed spray-dried nanosuspensions were … improve the solubility of poorly
water-soluble drugs [Citation1,… drying or freeze drying [Citation7–10]. The obtained products …

… The spray freeze-drying (SFD) technique has been previously established to … poorly
water-soluble drugs in our laboratory. A drug nanosuspension prepared through a wet-beads milling …

… been used to convert drug nanosuspensions into nanocomposite … both freeze drying and
spray drying can achieve high drug … alone, water-soluble polymers may not guarantee fast drug …

… instability, drug nanosuspensions are usually dried into … and time efficient compared to freeze
drying [32]. Hence, … as to how hydrophilic and freely water-soluble dispersants used in this …