[HTML][HTML] Desogestrel plus testosterone effectively suppresses spermatogenesis but also causes modest weight gain and high-density lipoprotein suppression

BD Anawalt, KL Herbst, AM Matsumoto, TMT Mulders… - Fertility and sterility, 2000 - Elsevier
… in achieving severe oligoazoospermia or azoospermia than exogenous testosteroneplus
testosterone caused significant suppression of serum HDL cholesterol levels and weight gain (…

… combined with testosterone as a potential male contraceptive: additive effects between desogestrel and testosterone enanthate in suppression of spermatogenesis …

FCW Wu, R Balasubramanian… - The Journal of …, 1999 - academic.oup.com
… further fall only in high density lipoprotein cholesterol to 22.6 ± … daily with T enanthate can
suppress spermatogenesis (19, 26), … Subjects in groups 1 and 3 noticed a modest increase in …

Oral desogestrel with testosterone pellets induces consistent suppression of spermatogenesis to azoospermia in both Caucasian and Chinese men

D Kinniburgh, H Zhu, L Cheng, AT Kicman… - Human …, 2002 - academic.oup.com
High-density lipoprotein cholesterol fell by 15% in Caucasian men, … ) Desogestrel plus
testosterone effectively suppresses spermatogenesis but also causes modest weight gain and …

A novel male contraceptive pill-patch combination: oral desogestrel and transdermal testosterone in the suppression of spermatogenesis in normal men

WM Hair, K Kitteridge, DB O'Connor… - The Journal of Clinical …, 2001 - academic.oup.com
… , eg reduction of high density lipoprotein cholesterol (HDL-C) … This gain persisted; the average
weight gain at the end of the … skin reaction, there was no reason to doubt the high degree …

Suppression of spermatogenesis by etonogestrel implants with depot testosterone: potential for long-acting male contraception

RA Anderson, D Kinniburgh… - The Journal of Clinical …, 2002 - academic.oup.com
… changes including a fall in high-density lipoprotein C (HDL-C) … of oral desogestrel, yet the
degree of spermatogenic suppression … of testosterone in the present study resulted in a modest

Investigation of hormonal male contraception in African men: suppression of spermatogenesis by oral desogestrel with depot testosterone

RA Anderson, ZM Van Der Spuy, OA Dada… - Human …, 2002 - academic.oup.com
… There were no significant changes in lipoprotein or haemoglobin concentrations in any …
desogestrel with depot testosterone is an effective regimen for suppression of spermatogenesis

A multicenter phase IIb study of a novel combination of intramuscular androgen (testosterone decanoate) and oral progestogen (etonogestrel) for male hormonal …

CJ Hay, BM Brady, M Zitzmann… - The Journal of …, 2005 - academic.oup.com
… ) and im testosterone decanoate (TD) on suppression of gonadotropins and spermatogenesis
as a … ; total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and low-density …

Depot testosterone with etonogestrel implants result in induction of azoospermia in all men for long-term contraception

BM Brady, M Walton, N Hollow, AT Kicman… - Human …, 2004 - academic.oup.com
… or decline in high-density lipoprotein cholesterol concentrations. … the implant preparation
but, as spermatogenic suppression was not … of both oral desogestrel and etonogestrel implants. …

… of testosterone and levonorgestrel significantly increases lean mass in healthy young men in 4 weeks, but attenuates a decrease in fat mass induced by testosterone …

KL Herbst, BD Anawalt, JK Amory… - The Journal of …, 2003 - academic.oup.com
… progestin is decreased serum high density lipoproteins and possibly increased low density
… effects between desogestrel and testosterone enanthate in suppression of spermatogenesis, …

Male hormonal contraception: potential risks and benefits

N Ilani, RS Swerdloff, C Wang - Reviews in Endocrine and Metabolic …, 2011 - Springer
… (LDL), high density lipoprotein cholesterol (HDL) or … providing adequate sperm suppression
for contraceptive … additively suppress spermatogenesis while keeping the testosterone dose …