… The Shc family of docking proteins is important … ShcC proteins in 46 neuroblastoma samples
and showed that a significantly higher level of ShcC protein is observed in neuroblastomas …

… , significantly impaired the survival, differentiation and motility of NB-39-nu cells by blocking
… SH2 domain of ShcC may be responsible for this unique function of ShcC, distinct from ShcA…

… of docking proteins, ShcA, ShcB and ShcC, play roles in … unique functions through the
binding to the ALK proteins. As … and ShcC play different roles in survival and differentiation of …

… , significantly impaired the survival, differentiation and … responsible for this unique function
of ShcC, distinct to the sustained … lated ShcC in neuroblastoma cells plays an essential role in …

… and often show spontaneous differentiation and regression. … hyperphosphorylated ShcC
in several neuroblastoma cell … of ALK in neuroblastoma cells may suggest distinct function of …

… To test this hypothesis, we generated two different NB cell … Furthermore, we have detected
abundant ShcC expression in NB … and ShcC phosphotyrosine docking proteins function in the …

… Finally, a distinct role of ShcC (SHC3) docking protein in the differentiation of NB has been
… In addition, we identified several genes reported in other studies to be regulated in different …

… This extension has provided p66ShcA with a distinct role from … Further insights into the roles
of Shc proteins in differentiation … The oncogenic effect of ShcC in neuroblastoma cells was …

… behind unique ShcC/protein interactions and signaling. … , ShcC might contribute to
neuroblastoma progression by inhibiting signaling pathways involved in neuronal cell differentiation …

… Finally, a distinct role of ShcC (SHC3) docking protein in the differentiation of NB has been
… In addition, we identified several genes reported in other studies to be regulated in different …