Dopamine D2 and adenosine A2A receptors regulate NMDA-mediated excitation in accumbens neurons through A2A–D2 receptor heteromerization
… heteromerization, one of the most studied heteromer in the central nervous system. Here, …
striatal neurons A 2A and D 2 receptors regulate NMDA-mediated neuronal excitation resulting …
striatal neurons A 2A and D 2 receptors regulate NMDA-mediated neuronal excitation resulting …
Allosteric mechanisms within the adenosine A2A–dopamine D2 receptor heterotetramer
… heteromers or forming heteromers with adenosine A 1 … As mentioned above, in the striatum,
stimulation of A 2A R … by the striato-pallidal neuron) seems to be restrained by a strong tonic …
stimulation of A 2A R … by the striato-pallidal neuron) seems to be restrained by a strong tonic …
Allosteric interactions between agonists and antagonists within the adenosine A2A receptor-dopamine D2 receptor heterotetramer
J Bonaventura, G Navarro… - Proceedings of the …, 2015 - National Acad Sciences
… species, and GPCR heteromers likely are constituted by heteromers of homodimers. The …
58261 on NMDA-mediated depolarized plateau potential on D 2 R-responsive neurons in rat …
58261 on NMDA-mediated depolarized plateau potential on D 2 R-responsive neurons in rat …
Evidence for the heterotetrameric structure of the adenosine A2A–dopamine D2 receptor complex
V Casadó-Anguera, J Bonaventura… - Biochemical Society …, 2016 - portlandpress.com
… key in the modulation of striatal neuronal function. We also review … new clues about how to
adjust the drug dosage to the … 1 R and dopamine D 3 receptor (D 3 R) heteromers, comprised …
adjust the drug dosage to the … 1 R and dopamine D 3 receptor (D 3 R) heteromers, comprised …
Essential Control of the Function of the Striatopallidal Neuron by Pre-coupled Complexes of Adenosine A2A-Dopamine D2 Receptor Heterotetramers and Adenylyl …
S Ferre, J Bonaventura, W Zhu… - Frontiers in …, 2018 - frontiersin.org
… can form A2AR-D2R heteromers. It was initially assumed that … been classically subdivided
into nucleus accumbens (NAc), … striatopallidal neuron activation using stimulation parameters …
into nucleus accumbens (NAc), … striatopallidal neuron activation using stimulation parameters …
Striatal astrocytic A2A-D2 receptor-receptor interactions and their role in neuropsychiatric disorders
… by adenosine A2A and dopamine D2 receptors on the plasma membrane of striatal neurons.
… Accordingly, A2A-D2 heteromers regulate NMDA-mediated firing in striatopallidal GABA …
… Accordingly, A2A-D2 heteromers regulate NMDA-mediated firing in striatopallidal GABA …
[HTML][HTML] Presynaptic adenosine receptor heteromers as key modulators of glutamatergic and dopaminergic neurotransmission in the striatum
… These heteromers control dopamine release by activation of … neuron is a main locus of
interaction of adenosine and … release upon cortico-striatal glutamatergic stimulation, we designed …
interaction of adenosine and … release upon cortico-striatal glutamatergic stimulation, we designed …
Dopamine D2 heteroreceptor complexes and their receptor–receptor interactions in ventral striatum: novel targets for antipsychotic drugs
K Fuxe, DO Borroto-Escuela, AO Tarakanov… - Progress in brain …, 2014 - Elsevier
… between A2A and D2 homomers and A2A–D2 heteromers after … of DA neurons and the
hypoactivity of NMDA-mediated … accumbens since the D2 protomer enhances OXT receptor …
hypoactivity of NMDA-mediated … accumbens since the D2 protomer enhances OXT receptor …
Glutamate mGlu5-adenosine A2A-dopamine D2 receptor interactions in the striatum. Implications for drug therapy in neuro-psychiatric disorders and drug abuse
… role of mGlu5-A2A-D2 receptor interactions in the modulation of … being a potentiation of
NMDA-mediated responses by … demonstrated heteromerization of mGlu5 and A2A receptors by …
NMDA-mediated responses by … demonstrated heteromerization of mGlu5 and A2A receptors by …
Adenosine A2A-D2 receptor-receptor interactions in putative heteromers in the regulation of the striato-pallidal gaba pathway: possible relevance for parkinson's …
S Beggiato, T Antonelli, MC Tomasini… - Current Protein and …, 2014 - ingentaconnect.com
… neurobiology of dopamine D2 and adenosine A2A receptors. … A2A/D2 heteromers on
striato-pallidal GABA neurons play in … to the stimulation of striatal adenosine A2A receptors. Thus, …
striato-pallidal GABA neurons play in … to the stimulation of striatal adenosine A2A receptors. Thus, …