… Our results suggest that down-regulation of alpha-2u globulin may be associated with an …
during diabetes. The decreased expression of A2-fragment in renal mitochondria of diabetic …

… , in an STZ-induced diabetic rat, alpha-2u globulin and its modified form are dysregulated
in renal mitochondria, … compared to more intact mitochondria found in non-alpha 2u-globulin …

… involved in the development of DN by a proteomic approach. … We found that the expression
of 3-hydroxy-3-methylglutaryl-CoA (HMG… -convertible HMG-CoA inside the mitochondria (25). …

… two-dimensional gel method. The proteins that were down-regulated with diabetes include
… On the other hand, proteins seen or predicted to be up-regulated include proteins involved …

… distributed in the cytosol, mitochondria, peroxisomes, and plasma (… of renal cortex from the
two mouse groups and found it to be … is increased in kidneys of STZ-induced diabetic rats (51), …

… groups and the control group were found and identified by 2-… 45,404 8.02 64 35 Down-regulation
Involved in the regulation … , mitochondrial 25,301 7.79 110 46 Down-regulation Involved …

… , whereas albumin and α-2u globulin were increased. Some of … food particles incubated in
water were seen on gels (data not … methods (3, 24), we also confirmed the proteomic data by …

… study the proteome-level changes in the OLETF rat kidney cortex… to dysfunction of
mitochondrion in OLETF rats, and promote … 36 differentially expressed proteins were found. Eight …

… Similar findings were observed in the renal glomeruli, in which mRNA of VEGF isoforms
120, 164, and 188 were detected (Figure 1C). Only VEGF 164 and 188 increased in the …

… phenomenological analysis (IPA) approach to subject DEGs and … , we found some typical
features of T2DM in ZDF rats, such as … A previous proteomic analysis on diabetic retinas (55) …