… rat livers to PB feeding during the promotion phase was evident from the ex pression of the
P-450 isoforms. Pubertal rats receiving DEN initiation … to be normally expressed lost the ability …

… of the stages in tumor development will be presented first. … into a stage of initiation as produced
by the direct action of a … to rat liver nuclear DNA when fed as a promoting agent [151]. As …

… of AHF present in livers of male rats promoted by this agent … hallmark of the final stage of
progression in the development of … the specific action of the agent at one or more of the stages of …

… EAF) and nodules in the liver of Wistar rats initiated by diethylnitrosamine. The effects of 5-adenosyl-…
, between 4 and 9 weeks after initiation, to a phase in which progressive decrease in …

… liver tumors in rats and mice. A number of these agents appear to function through tumor
promoting rather than initiating … is the differential growth effect that liver tumor promoting agents …

… The initiation–promotion model of cancer development used … The initiation stage of cancer
development can be produced by … If rats are older than 2 weeks, a tumor promoter is required …

… development through clonal expansion of already initiated … into the stages of initiation,
promotion and progression. … 2-stage liver carcinogenesis model in which rats were initiated …

… of initiated cells induced by 200 mg diethylnitrosamine/kg may even protect rats against the
highly toxic effect … According to the multi-stage development of liver tumors one would further …

… the action of specific carcinogenic agents is considered in relation to the stages of cancer
development, initiation, promotion… , the stimulation of growth and altered genetic expression by …

… The effect of TCDD on TGFa expression in liver cells was … the effects detected in our study
are due to the promotion with … regulator in the regenerative phase after partial hepatectomy …