… The present work studied the effects of amiodarone (AMD) and iopanoic acid (IA) on the
conversion of thyroxine (T4) to tri-iodothyronine (T3) by rat myocardium. In vivo: male Wistar rats …

… is decreased and that 5'-deiodination could be affected. In … on rabbit myocardial B
adrenoceptors and thyroid hormones. … of [125I] -thyroxine and [125I]-triiodothyronine of high …

… a drug-induced inhibition of the 5'-deiodination of T4 to T3 (6, … This effect is probably even
more marked in the myocardium, … tri-iodothyronine and reverse tri-iodothyronine from thyroxine …

… amiodarone on serum thyroid hormone and thyrotropin (TSH) concentrations and hepatic
and pituitary 5' deiodination of thyroxine (… MB: Effect of amiodarone on serum triiodothyronine, …

… , the enzyme that catalyses the 5'-deiodination off T4 into T3 … and depression of myocardial
oxygen consumption, but the … WM 1997 Tri-iodothyronine prevents the amiodarone-inducedd …

… However, it is widely accepted that the effects of AMIO on thyroid hormone plasma …
concentrations of 2 μg and 10 μg for rat D1 and human D2 assays respectively. A mix of DAB and …

… The effects of amiodarone on thyroid hormone economy are, at … effects of amiodarone/DEA
have been attributed to their ability to decrease thyroid hormone signaling in the myocardium, …

… heart failure develop as a result of myocardial infarction (218)), or … of amiodarone on TSH
synthesis and secretion at the … did not have any negative effect on rat D1 activity, demonstrating …

… The inhibitory effects of amiodarone on thyroid hormone … Deiodination of the outer phenolic
ring (5'-deiodination) of … receptors and triiodothyronine concentration in pig myocardium after …

… of action is to block myocardial potassium channels, but it … dose of amiodarone by intravenous
infusion, TSH is the first … Amiodarone also inhibits the 5’-deiodination of T4 to T3 in the …