… hypoxic rat vascular endothelial-smooth muscle cell co-culture model. Evaluation of ET-1
mRNA level in smooth muscle and endothelial cells … that as the time of hypoxia lengthened, the …

… by increased availability of both ligand and cognate receptors, … Down-regulation of Flk-1
mRNA has also been shown in … Endothelin receptors in rat liver: lipocytes as a contractile target …

… The decreased adhesion between vascular endothelial cells … of hypoxia-inducible factor-1α
and vascular endothelial growth … up-regulation of ephrin-B2 and down-regulation of EphB3 (…

… release by HSC of vascular endothelial growth factor (VEGF), matrix … Down-regulation Vascular
cell adhesion molecule 1 … Culture of these cells under hypoxia increased VEGF secretion …

… SIRT1 activation leads to the down regulation of nuclear … as, vascular endothelial growth
factor (VEGF), hypoxia − induced … -like ligand 4) DLL4/Notch signals and indicate a regulatory …

… 28], restoration of eNOS down-regulation [26], and modulation … microvascular endothelial
cells showed that hypoxia followed … of vascular endothelial dysfunction in myocardial I/R injury …

… to a range of stimuli including hypoxia, vasoactive hormones, … specific cell types: vascular
endothelium and endothelial cells … a sustained down regulation of endothelin receptors and cel…

… as vascular endothelial growth factor (VEGF) and its receptors.21, … In the chronically hypoxic
rat model of pulmonary … to either up- or down-regulation of inhibitors of the cell cycle (cdk …

… of vascular endothelial growth factor and endothelin in the … by up-regulating the levels of
NIC and its ligand expression, … hypoxia and the down-regulation of miR-155 was observed in …

… -1 can regulate the adaptive cellular responses to hypoxia by … of pulmonary arterial endothelial
cells causes vascular … reduced intimal proliferation and down-regulation of E-selectin and …