Everolimus: side effect profile and management of toxicities in breast cancer

E Paplomata, A Zelnak, R O'Regan - Breast cancer research and treatment, 2013 - Springer
… This review will focus on the side effect profile of everolimusmanagement of frequently
encountered toxicities. Given, the impressive efficacy of everolimus in metastatic breast cancer, it …

[HTML][HTML] Adverse event management in patients with advanced cancer receiving oral everolimus: focus on breast cancer

M Aapro, F Andre, K Blackwell, E Calvo, M Jahanzeb… - Annals of oncology, 2014 - Elsevier
… The safety profile and protocols for toxicity management are well established. The class-effect
adverse event profile observed with everolimus plus endocrine therapy in breast cancer is …

[HTML][HTML] Everolimus therapy and sideeffects: A systematic review and meta‑analysis

C Arena, ME Bizzoca… - International …, 2021 - … .spandidos-publications.com
… MESH terms: ‘everolimus’ AND ‘sideeffects’ OR ‘toxicities’ OR ‘… Everolimus in particular,
is clinically used for the treatment of … 2 (HER-2)-negative breast cancer, renal cell carcinoma, …

Novel agents and associated toxicities of inhibitors of the pi3k/Akt/mtor pathway for the treatment of breast cancer

S Chia, S Gandhi, AA Joy, S Edwards, M Gorr… - Current oncology, 2015 - mdpi.com
… The most common unique adverse events observed in everolimus clinical trials in breast
cancer … At that point, the nurse makes an assessment for early everolimus side effects such as …

Safety, efficacy, and patient acceptability of everolimus in the treatment of breast cancer

L Lousberg, G Jerusalem - Breast Cancer: Basic and …, 2016 - journals.sagepub.com
… can modify plasmatic concentrations of everolimus and affect its efficacy and toxicity. The
patient's … Cost, side effect profile, and disease aggressiveness at time of progression after each …

Everolimus-induced hematologic changes in patients with metastatic breast cancer

A Chen, L Chen, A Al-Qaisi, E Romond, M Awasthi… - … Breast Cancer, 2015 - Elsevier
… and well known side effect of using mTOR inhibitors. The spectrum of hematologic toxicities
… rather ubiquitous hematologic toxicities encountered during everolimus treatment, the most …

Everolimus in the treatment of hormone receptor-positive breast cancer

M Chavez-MacGregor… - Expert opinion on …, 2012 - Taylor & Francis
… the use of everolimus in HR-positive breast cancer patients in … but also describe in detail
the side effect profile of this drug. … breast cancer; it also demonstrated that despite the toxicity

[HTML][HTML] Dosing and safety implications for oncologists when administering everolimus to patients with hormone receptor-positive breast cancer

HS Rugo - Clinical Breast Cancer, 2016 - Elsevier
… be maintained despite everolimus dose reductions required to manage toxicities, such as …
for early detection and management of toxicity. The appropriate management of AEs will …

[HTML][HTML] Efficacy and toxicity of everolimus plus exemestane in third and later lines treatment of hormone receptor-positive, HER2-negative metastatic breast cancer

F Yıldız, B Öksüzoğlu - Journal of Surgery and Medicine, 2020 - dergipark.org.tr
breast cancer (MBC). The aim of this study is to evaluate the efficacy and toxicity of everolimus
… One of the most common side effects of everolimus plus exemestane is stomatitis, which …

Targeting the mammalian target of rapamycin pathway with everolimus: Implications for the management of metastatic breast cancer

VC Ng, JJ Johnson, S Cuellar - Journal of Oncology …, 2015 - journals.sagepub.com
… in breast cancer cells. The role of everolimus in breast cancer was established in the
BreastEverolimus toxicities are generally mild as reported in published literature, however …