Evidence that differentiation-inducing factor-1 controls chemotaxis and cell differentiation, at least in part, via mitochondria in D. discoideum
Y Kubohara, H Kikuchi, VH Nguyen… - Biology …, 2017 - journals.biologists.com
… -1)] is an important regulator of cell differentiation and chemotaxis in the development of the
… cell differentiation and modulate chemotaxis, at least in part, by disturbing mitochondrial …
… cell differentiation and modulate chemotaxis, at least in part, by disturbing mitochondrial …
[HTML][HTML] Differentiation-Inducing Factor-1 and -2 Function also as Modulators for Dictyostelium Chemotaxis
H Kuwayama, Y Kubohara - PLoS One, 2009 - journals.plos.org
… Various indirect evidence suggests that DIFs may have novel … Furthermore, our findings
suggest that cell differentiation … as drugs to control mammalian chemotaxis for basic research …
suggest that cell differentiation … as drugs to control mammalian chemotaxis for basic research …
[HTML][HTML] Control of Cell Differentiation by Mitochondria, Typically Evidenced in Dictyostelium Development
Y Maeda, J Chida - Biomolecules, 2013 - mdpi.com
… multicellular structures by means of chemotaxis toward 3’,5’-… novel protein that binds to tumor
necrosis factor 1 (TNF-1) [28]… It has been shown that differentiation-inducing factors (DIFs) …
necrosis factor 1 (TNF-1) [28]… It has been shown that differentiation-inducing factors (DIFs) …
The Dictyostelium model for mitochondrial biology and disease
XG Pearce, SJ Annesley, PR Fisher - The International Journal of …, 2019 - ijdb.ehu.es
… evidence of mitochondria’s role in differentiation … differentiation-inducing factors (DIF) (Kubohara
et al., 2017, Thompson and Kay, 2000). These DIFs also are involved in chemotaxis in D…
et al., 2017, Thompson and Kay, 2000). These DIFs also are involved in chemotaxis in D…
[HTML][HTML] Derivatives of Differentiation-Inducing Factor 1 Differentially Control Chemotaxis and Stalk Cell Differentiation in Dictyostelium discoideum
H Kuwayama, H Kikuchi, Y Kubohara - Biology, 2023 - mdpi.com
… differentially control stalk cell differentiation and chemotaxis. We … have at least three receptors:
DR-1D, responsible for stalk cell … to mitochondria, suggesting that DIF-1 controls stalk cell …
DR-1D, responsible for stalk cell … to mitochondria, suggesting that DIF-1 controls stalk cell …
[HTML][HTML] Pharmacological Evidence That Dictyostelium Differentiation-Inducing Factor 1 Promotes Glucose Uptake Partly via an Increase in Intracellular cAMP …
Y Kubohara, Y Fukunaga, H Kikuchi, H Kuwayama - Molecules, 2023 - mdpi.com
… differentiation, cell death, chemotaxis, and morphogenesis, … isolated as a stalk cell
differentiation-inducing factor in D. … a mitochondrial uncoupler and can promote glucose uptake, at …
differentiation-inducing factor in D. … a mitochondrial uncoupler and can promote glucose uptake, at …
The Dictyostelium prestalk inducer differentiation-inducing factor-1 (DIF-1) triggers unexpectedly complex global phosphorylation changes
… of DIF-1 on chemotaxis to cAMP. All MS data are available … been suspected; we present
evidence suggesting that DIF-1 … In addition to potential control of cellular signaling via protein …
evidence suggesting that DIF-1 … In addition to potential control of cellular signaling via protein …
On the Evolutionary Conservation of the Cell Death Pathway: Mitochondrial Release of an Apoptosis-inducing Factor duringDictyostelium discoideum Cell Death
D Arnoult, I Tatischeff, J Estaquier… - … biology of the cell, 2001 - Am Soc Cell Biol
… conservation of at least part of the cell death pathway in … cell death induced by
differentiation-inducing factor-1 (DIF-1). … involve cell chemotaxis and aggregation and …
differentiation-inducing factor-1 (DIF-1). … involve cell chemotaxis and aggregation and …
[HTML][HTML] Dictyostelium: An Important Source of Structural and Functional Diversity in Drug Discovery
Y Kubohara, H Kikuchi - Cells, 2018 - mdpi.com
… and functions of polyketide differentiation-inducing factor-1, a … as modulators for Dictyostelium
chemotactic cell movement … 20 µM induces a loss of mitochondrial membrane potential, …
chemotactic cell movement … 20 µM induces a loss of mitochondrial membrane potential, …
[HTML][HTML] Differentiation-inducing factor 1 activates cofilin through pyridoxal phosphatase and AMP-activated protein kinase, resulting in mitochondrial fission
T Inoue, K Miura, R Han, F Seto-Tetsuo… - Journal of …, 2023 - Elsevier
… produced by Dictyostelium discoideum that inhibits the … exhausted, unicellular cells
differentiate into multicellular fruiting … was performed using anti-HA antibody or control mouse IgG …
differentiate into multicellular fruiting … was performed using anti-HA antibody or control mouse IgG …