… -coding gene in the genome. Here we used exome sequencing 1 to explore protein-altering
variants and their consequences in 454,787 participants in the UK Biobank study 2 . We …

… (WGS) provides a comprehensive view of the genome, … -genome sequencing of 490,640
UK Biobank participants, building on previous genotyping1 and whole-exome sequencing (WES…

… method that quickly and accurately processes large sequencing datasets and applied it to
UK Biobank (UKB) whole-genome and whole-exome sequencing data. We demonstrate that …

… data for 200,000 UK Biobank participants identified two genes affecting risk of hypertension
… Exome sequencing and analysis of 454,787 UK Biobank participants. Nature. 2021;599(…

… , we analyzed exome and health data from 454,787 participants of the UK Biobank (UKB). It
has … We also removed participants with self-reported substance abuse, psychotic condition or …

… research was conducted using the UK Biobank resource, under application 14631. We thank
the UK Biobank participants and coordinators for the dataset. This study was supported by …

… We interrogated 454,787 whole exome sequences available in the UKBB to characterize
the diversity of CFTR variants across six ancestries [AFR, CSA, EAS, EUR, AMR, and MID] and …

… analysis of rare coding variants observed in 200,000 exome-sequenced UK Biobank participants
… at exome-wide significance: LDLR, PCSK9, ANGPTL3 and IFITM5 [1]. The report of that …

… Our study did have several limitations. First, even with the large sample size provided by exome
sequencing in UK Biobank, we … Exome sequencing and analysis of 454,787 UK Biobank …

… The recently released whole-exome sequencing data in UKB … we analyzed exome sequencing,
survey, questionnaire, and electronic health record (EHR) data from 454,787 participants …