Flavonoids, Dietary-derived Inhibitors of Cell Proliferation and in Vitro Angiogenesis

T Fotsis, MS Pepper, E Aktas, S Breit, S Rasku… - Cancer research, 1997 - AACR
… genistein as a potent inhibitor of cell proliferation and in vitro angiogenesis (10, 11). Further
… of flavonoids, a group of compounds that are isomeric to isoflavonoids. Flavonoid aglycones …

Quercetin, a dietary-derived flavonoid, possesses antiangiogenic potential

W Tan, L Lin, M Li, YX Zhang, Y Tong, D Xiao… - European journal of …, 2003 - Elsevier
angiogenic factors include vascular endothelial cell growth … When screening tumor
angiogenesis inhibitors, we found that … the potential of quercetin as an inhibitor of angiogenesis. …

Antiangiogenic mechanisms of diet-derived polyphenols

Y Cao, R Cao, E Bråkenhielm - The Journal of Nutritional Biochemistry, 2002 - Elsevier
… It weakly inhibits endothelial cell proliferation and migration although the mechanisms are
still unclear [22]. However, this flavonoid seems to be a potent angiogenesis inhibitor in vivo. …

Antiangiogenic effects of flavonoids and chalcones

J Mojzis, L Varinska, G Mojzisova, I Kostova… - Pharmacological …, 2008 - Elsevier
Angiogenic stimuli cause increased endothelial cell … Endothelial cell proliferation occurs
early in angiogenesis, and … promotes endothelial cell survival and proliferation through …

Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vitro angiogenesis

T Fotsis, M Pepper, H Adlercreutz, T Hase… - The Journal of …, 1995 - Elsevier
… be associated with dietary derived angiogenesis inhib itors, … to inhibit the proliferation of
vascular endothelial cells. One of the … and inhibited endothelial cell proliferation and in vitro an …

The dietary flavones apigenin and luteolin impair smooth muscle cell migration and VEGF expression through inhibition of PDGFR-β phosphorylation

S Lamy, V Bédard, D Labbé, H Sartelet… - Cancer prevention …, 2008 - AACR
cell function result in impaired angiogenesis. Overall, these results identify apigenin and
luteolin as dietary-derived inhibitors … Among these, polyphenols such as flavonoids are found at …

7Phytoestrogens and inhibition of angiogenesis

T Fotsis, MS Pepper, R Montesano, E Aktas… - Bailliere's clinical …, 1998 - Elsevier
flavonoids as inhibitors of angiogenesis, we tested selected flavonoids in the in vitro angiogenesis
… , Aktas E et al (1997) Flavonoids dietary-derived inhibitors of cell proliferation and in …

[HTML][HTML] Antiangiogenic phytochemicals constituent of diet as promising candidates for chemoprevention of cancer

AD Marrero, AR Quesada, B Martínez-Poveda… - Antioxidants, 2022 - mdpi.com
… compounds belonging to the flavonoid subclass, mainly found … to its capacity to induce cell
cycle arrest in cancer cells [62,63… is a multitarget inhibitor of angiogenesis in vitro and in vivo […

[HTML][HTML] Tumor angiogenesis as a target for dietary cancer prevention

WW Li, VW Li, M Hutnik, AS Chiou - Journal of oncology, 2012 - hindawi.com
… potent tea flavonoid that specifically inhibits endothelial cellangiogenesis inhibition,
induction of apoptosis, G2 cell cycle … antiangiogenic activity in a number of other dietaryderived

Diet-derived polyphenols inhibit angiogenesis by modulating the interleukin-6/STAT3 pathway

S Lamy, N Akla, A Ouanouki, S Lord-Dufour… - Experimental cell …, 2012 - Elsevier
… in cancer progression including tumor cell growth, survival and angiogenesis. In addition to
… polyphenols against angiogenesis and highlight the potency of dietary-derived polyphenols …