… endothelial cell surfaces responsible for galectin-3-induced secretion of metastasis-promoting
cytokines… We conclude that CD146/MCAM interactions with circulating galectin-3 may …

… metastasis-promoting cytokines by endothelial cells [16]. … structures of cell membrane
glycoproteins including MCAM, showed to … the galectin-3–MCAM interaction on cell surface affects …

… and the angiostimulatory protein vascular endothelial growth factor (… endothelial cell surface,
including CD31 (PECAM-1), CD146 … The interaction of galectin-3 with CD146 was shown to …

… for the metastasis-promoting effect of galectin-3. This thesis … Galectin-3 also induces
endothelial cell surface adhesion molecule … galectin-3 was found to interact with CD146 (MUC18) …

… Due to the high sequence homology between MUC18 with cell … of CD146 expression
abolishes Galectin-3-induced secretion of metastasis-promoting cytokine from the endothelial cells. …

… MCAM, also known as MUC18) on the surface of vascular … of cytokine secretion mediated
by PNA and galectin-3. The … Binding of MCAM by galectin-3 induces MCAM cell surface …

… This membrane glycoprotein is also found as a circulating … Similarly, in lung vascular
endothelial cells from CD146KO … inflammatory cytokines and increases the ratio of the CD146 + …

… CD146 to promote cytokine secretion and mediate … Gal-3 interactions to the cell surface
adhesion receptor CD146, in … the collagen-like domain of galectin-3 in vascular endothelial cells …

… to the cell surface, extracellular space and circulation without the … for galectin-3-induced
secretion of metastasis-promoting … The interaction of galectin-3 with endothelial CD146/MCAM in …

… immunofluorescence staining of vascular endothelial (VE)-… nucleus and on the cell
surface and is also secreted into the … cell interactions, and recruitment of metastasis-promoting …