Halogenated pentamethine cyanine dyes exhibiting high fidelity for G-quadruplex DNA
R Nanjunda, EA Owens, L Mickelson… - Bioorganic & medicinal …, 2012 - Elsevier
… The tricationic pentamethine structure was then synthesized … In summary, pentamethine
cyanines with multiple halogen … and with very high selectivity over duplex DNA. The selectivity of …
cyanines with multiple halogen … and with very high selectivity over duplex DNA. The selectivity of …
[HTML][HTML] Selective G-quadruplex DNA recognition by a new class of designed cyanines
… by halogenation of cyanines, … various pentamethine cyanine dyes with the telomeric and
the c-myc oncogenic quadruplex forming sequences [18]. The pentamethine analogs exhibited …
the c-myc oncogenic quadruplex forming sequences [18]. The pentamethine analogs exhibited …
Synthetic Development of Cyanine Dyes and Investigation of Their Interaction with Duplex DNA
C Holder - 2016 - scholarworks.gsu.edu
… tri-, and pentamethine cyanine dyes … DNA. Chapter 1 [15] and 2 present the synthesis and
optical properties of monomethine cyanine dyes and investigates their unique ability to exhibit …
optical properties of monomethine cyanine dyes and investigates their unique ability to exhibit …
Synthetic Development of the Tri-and Pentamethine Cyanine Chromophore for Biomolecular Interactions
EA Owens - 2012 - scholarworks.gsu.edu
… preparation of halogenated carbocyanine dyes that display … bind G-quadruplex DNA with
selectivity over duplex DNA and … DNA and maintained the high fidelity discovered by the other …
selectivity over duplex DNA and … DNA and maintained the high fidelity discovered by the other …
Second generation G-quadruplex stabilizing trimethine cyanines
EA Owens, HT Huynh, EM Stroeva… - Bioconjugate …, 2019 - ACS Publications
… , the cyanine dyes that bind selectively to G-quadruplex … reported pentamethine and symmetric
trimethine cyanines … Fischer-indole reaction with halogenated phenyl hydrazine salts and …
trimethine cyanines … Fischer-indole reaction with halogenated phenyl hydrazine salts and …
[PDF][PDF] Recent developments in G-quadruplex probes
DL Ma, Z Zhang, M Wang, L Lu, HJ Zhong… - Chemistry & Biology, 2015 - cell.com
… Interestingly, the pentamethine cyanines with multiple halogen … of these cyanine dyes as
G-quadruplex probes. While … In UV-Vis spectroscopy experiments, both complexes exhibited …
G-quadruplex probes. While … In UV-Vis spectroscopy experiments, both complexes exhibited …
[HTML][HTML] DNA photocleavage in the near-infrared wavelength range by 2-quinolinium dicarbocyanine dyes
… syntheses of two pentamethine cyanine dyes containing … pentamethine linker to connect
two 2-quinolinium rings, here we synthesized two symmetrical dicarbocyanine dyes that exhibit …
two 2-quinolinium rings, here we synthesized two symmetrical dicarbocyanine dyes that exhibit …
Unprecedented DNA Photocleavage Mediated by Quinolinium Pentamethine Carbocyanine Dyes in the NIR Wavelength Range
EO Ahoulou - 2021 - scholarworks.gsu.edu
… ) quinolinium pentamethine carbocyanine dyes substituted … We are interested in developing
these cyanine dyes as … and studied numerous cyanine dyes that exhibit the ability of …
these cyanine dyes as … and studied numerous cyanine dyes that exhibit the ability of …
Synthesis, Characterization, Optical Properties and DNA Cleavage Study of Symmetrical Pentamethine Cyanine Dyes Containing Quinoline Moieties
K Ilina - 2020 - scholarworks.gsu.edu
… The CD spectra of the parallel G-quadruplex exhibits a specific positive peak at 265 nm and
… on the production of Gquadruplex structures. Such a G-quadruplex probe can disclose the …
… on the production of Gquadruplex structures. Such a G-quadruplex probe can disclose the …
Comprehensive thermodynamic profiling for the binding of a G-quadruplex selective indoloquinoline
A Funke, K Weisz - The Journal of Physical Chemistry B, 2017 - ACS Publications
… Both binding enthalpy ΔH and binding entropy ΔS exhibit a … ligand and G-quadruplex
substantially contribute in addition to … of halogenated cyanine dyes to the c-MYC quadruplex. (39) …
substantially contribute in addition to … of halogenated cyanine dyes to the c-MYC quadruplex. (39) …