Halogenated pentamethine cyanine dyes exhibiting high fidelity for G-quadruplex DNA

R Nanjunda, EA Owens, L Mickelson… - Bioorganic & medicinal …, 2012 - Elsevier
… The tricationic pentamethine structure was then synthesized … In summary, pentamethine
cyanines with multiple halogen … and with very high selectivity over duplex DNA. The selectivity of …

[HTML][HTML] Selective G-quadruplex DNA recognition by a new class of designed cyanines

R Nanjunda, EA Owens, L Mickelson, TL Dost… - Molecules, 2013 - mdpi.com
… by halogenation of cyanines, … various pentamethine cyanine dyes with the telomeric and
the c-myc oncogenic quadruplex forming sequences [18]. The pentamethine analogs exhibited

Synthetic Development of Cyanine Dyes and Investigation of Their Interaction with Duplex DNA

C Holder - 2016 - scholarworks.gsu.edu
… tri-, and pentamethine cyanine dyesDNA. Chapter 1 [15] and 2 present the synthesis and
optical properties of monomethine cyanine dyes and investigates their unique ability to exhibit

Synthetic Development of the Tri-and Pentamethine Cyanine Chromophore for Biomolecular Interactions

EA Owens - 2012 - scholarworks.gsu.edu
… preparation of halogenated carbocyanine dyes that display … bind G-quadruplex DNA with
selectivity over duplex DNA and … DNA and maintained the high fidelity discovered by the other …

Second generation G-quadruplex stabilizing trimethine cyanines

EA Owens, HT Huynh, EM Stroeva… - Bioconjugate …, 2019 - ACS Publications
… , the cyanine dyes that bind selectively to G-quadruplex … reported pentamethine and symmetric
trimethine cyanines … Fischer-indole reaction with halogenated phenyl hydrazine salts and …

[PDF][PDF] Recent developments in G-quadruplex probes

DL Ma, Z Zhang, M Wang, L Lu, HJ Zhong… - Chemistry & Biology, 2015 - cell.com
… Interestingly, the pentamethine cyanines with multiple halogen … of these cyanine dyes as
G-quadruplex probes. While … In UV-Vis spectroscopy experiments, both complexes exhibited

[HTML][HTML] DNA photocleavage in the near-infrared wavelength range by 2-quinolinium dicarbocyanine dyes

EO Ahoulou, KK Drinkard, K Basnet, A St. Lorenz… - Molecules, 2020 - mdpi.com
… syntheses of two pentamethine cyanine dyes containing … pentamethine linker to connect
two 2-quinolinium rings, here we synthesized two symmetrical dicarbocyanine dyes that exhibit

Unprecedented DNA Photocleavage Mediated by Quinolinium Pentamethine Carbocyanine Dyes in the NIR Wavelength Range

EO Ahoulou - 2021 - scholarworks.gsu.edu
… ) quinolinium pentamethine carbocyanine dyes substituted … We are interested in developing
these cyanine dyes as … and studied numerous cyanine dyes that exhibit the ability of …

Synthesis, Characterization, Optical Properties and DNA Cleavage Study of Symmetrical Pentamethine Cyanine Dyes Containing Quinoline Moieties

K Ilina - 2020 - scholarworks.gsu.edu
… The CD spectra of the parallel G-quadruplex exhibits a specific positive peak at 265 nm and
… on the production of Gquadruplex structures. Such a G-quadruplex probe can disclose the …

Comprehensive thermodynamic profiling for the binding of a G-quadruplex selective indoloquinoline

A Funke, K Weisz - The Journal of Physical Chemistry B, 2017 - ACS Publications
… Both binding enthalpy ΔH and binding entropy ΔS exhibit a … ligand and G-quadruplex
substantially contribute in addition to … of halogenated cyanine dyes to the c-MYC quadruplex. (39) …