… This article reviews these various connective tissue disorders, describes the underlying …
on tissue repair, (WOUND REP REG 1997;5:3-11) The heritable disorders of connective tissue …

… these disorders, and recent reviews have compared clinical features of subsets of the … the
key clinical and genetic features of heritable disorders of connective tissue. Marfan syndrome …

… for heritable connective tissue disorders and or acquired musculoskeletal conditions without
a … Joint hypermobility and the heritable disorders of connective tissue: clinical and empirical …

… the clinician to search for underlying hereditary disorders of connective tissues. In this article,
we … , and genetic screening of the more common hereditary disorders of connective tissues, …

In 1896 Antoine Marfan described a musculoskeletal disorder in a 5-year-old girl producing
excessive lengthening and slenderness of the arms and legs. The fingers were flexed by …

… Important, however, is the realization that JHM may provide the first insight as to the presence
of one of the heritable disorders of connective tissue (HDCT). Further enquiry may reveal …

… The disorders discussed in this chapter all affect the connective or supporting tissues of the
body. However, nearly all these diseases affect many systems of the body and could equally …

… This study includes predictive genetic testing of relatives for a known family mutation, which
increases the likelihood of positive findings. In the present study, NGS analysis was offered …

… Sixty-seven genes were selected through a review of the published literature for the diagnosis
of connective tissue diseases ( Table 2 ). Targeted capture was performed using SeqCap …

… Heritable connective tissue disorders comprise a wide range of pleiotropic diseases that
result from genetic … a significant proportion of human genetic diseases. They affect mainly the …