High-performance method to detection of Klebsiella pneumoniae Carbapenemase in Enterobacterales by LC-MS/MS

OA Lovison, RB Rau, D Lima-Morales… - Brazilian Journal of …, 2020 - Springer
… a LC-MS/MS method to direct detection of KPC protein in clinical isolates based on a previously
published study [22]. Method … variety of Enterobacterales harboring the most prevalent …

Rapid LCMS/MS detection of different carbapenemase types in carbapenemase-producing Enterobacterales

…, N Chen, Y Ye, Y Wang, F Wu, K Wang… - European Journal of …, 2022 - Springer
… beta-lactamases [mostly Klebsiella pneumoniae carbapenemase (KPC)]… detection of
carbapenemase-producing Enterobacterales (… Ultra-high-performance liquid …

Rapid detection of carbapenemase activity through monitoring ertapenem hydrolysis in Enterobacteriaceae with LCMS/MS

DR Peaper, MV Kulkarni, AN Tichy, M Jarvis… - Bioanalysis, 2013 - Future Science
detected by LCMS/MS. (B) Hydrolyzed ertapenem, prepared by incubation of ertapenem
with Klebsiella pneumoniae carbapenemase-… in tryptic soy broth and detected by LCMS/MS. …

[HTML][HTML] Molecular phenotyping approaches for the detection and monitoring of carbapenem-resistant Enterobacteriaceae by mass spectrometry

B Dixon, WM Ahmed, T Felton, SJ Fowler - … and Advances in the Clinical lab, 2022 - Elsevier
… ranges, with Klebsiella pneumoniae carbapenemases (KPCs… Top-down LC-MS/MS methods
for the detection of intact KPC … β-lactam resistance and Enterobacterales, provide strong …

[HTML][HTML] Performance evaluation of three automated identification systems in detecting carbapenem-resistant Enterobacteriaceae

Q He, W Chen, L Huang, Q Lin, J Zhang, R Liu… - Annals of clinical …, 2016 - Springer
… 81 CRE isolates carried carbapenemase genes, including 23 (… Notably, one Klebsiella
pneumoniae isolate produced both IMP… Klebsiella pneumoniae carbapenemase (KPC) were first …

[HTML][HTML] MALDI-TOF MS based carbapenemase detection from culture isolates and from positive blood culture vials

B Ghebremedhin, A Halstenbach, M Smiljanic… - Annals of clinical …, 2016 - Springer
… in single Enterobacter cloacae isolate whereas, the NDM variants, NDM-1 or NDM-6, were
carried by Escherichia coli, Klebsiella pneumoniae and E. cloacae isolates. The OXA variants …

… /Pharmacodynamic Analysis of the Efficacy of the Cefepime/Nacubactam Combination Against β-Lactamase-Producing Enterobacterales Based on the Instantaneous …

…, VTG Chuang, Y Enoki, K Taguchi, K Matsumoto - Pharmaceutical …, 2023 - Springer
… class A (Klebsiella pneumoniae carbapenemase [KPC] and … until analysis using high-performance
liquid chromatography-… measured using a validated LCMS/MS method (Table S1). …

[HTML][HTML] … and Pharmacodynamic Analysis of the Oxacephem Antibiotic Flomoxef against Extended-Spectrum β-Lactamase-Producing Enterobacterales from Dogs

M Kusumoto, M Jitsuiki, T Motegi, K Harada - International Journal of …, 2024 - mdpi.com
… Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis, … In the LC-MS/MS method
established in this study, high … LCMS/MS was performed on a high-performance liquid …

Simultaneous determination of ceftazidime and avibactam in human plasma and cerebrospinal fluid by high-performance liquid chromatography–tandem mass …

Q Wang, Y Zheng, L Liu, P Ji, W Jiang, J Zhao… - Analytical …, 2023 - Taylor & Francis
… The samples were analyzed by the validated LC-MS/MS method. … with infections caused
by Klebsiella pneumoniae carbapenemase-producing K. pneumoniae. Clinical Infectious …

[HTML][HTML] Fast and Sensitive Method for Simultaneous Quantification of Meropenem and Vaborbactam in Human Plasma Microsamples by Liquid Chromatography …

R Barone, M Conti, B Giorgi, M Gatti, PG Cojutti, P Viale… - Antibiotics, 2023 - mdpi.com
… It shows good in vitro activity against Enterobacterales … , and simple LC-MS/MS method for
quantifying simultaneously … Thanks to its high performance and reliability, this method may …